Jim Conroy as Quincy Magoo (voice)

Dylan Sprouse as Justin Magoo (voice)

Cole Sprouse as Brad Landry (voice)

Alyson Stoner as Lorelei Tan Gu (voice)

Chris Parnell as Cole Fusion / Ninja (voice)

Kenny Mayne as Kenny Mayne (voice)

Jeff Bennett as Sid / Guard / Evil Mustache Cabal (voice)

Rodger Bumpass as General Smith / Driver / Mastermind (voice)

Maile Flanagan as Aliga-Tory / Orangu-Tammy (voice)

Lloyd Floyd as Tan Gu (voice)

Jennifer Hale as Leslie Destructo / Agent L / Dutch Boy (voice)

Tom Kenny as Dr. Malicio / Soldier (voice)

Ryan Bollman as Corporal Hayes / Biker (voice)

Candi Milo as Gor-Illiana / McBarker / Sid's Mom (voice)

April Stewart as Weas-Elizabeth / Girl with Phone (voice)

Jim Ward as General Bonkopp / Movie Announcer / Voice on Radio (voice)

Susan Boyajian as (voice)

Bob Joles as (voice)

Hope Levy as (voice)

Michael Stanton as (voice)

Rob Tinkler as (voice)

Fred Travalena as (voice)

Wally Wingert as (voice)