Tim Curry as Johnny LaGuardia

Trini Alvarado as Pamela Pearl

Robin Johnson as Nicky Marotta

Peter Coffield as David Pearl

Herbert Berghof as Dr. Huber

David Margulies as Dr. Zymansky

Anna Maria Horsford as Rosie Washington

Michael Margotta as JoJo

J.C. Quinn as Simon

Miguel Piñero as Roberto

Ronald "Smokey" Stevens as Heavy

Billy Mernit as Blondell

Paul Sass as Blondell

Artie Weinstein as Blondell

Tim Choate as Eastman

Elizabeth Peña as Disco Hostess

Kathy Lojac as Nurse Joan

Susan Merson as Nurse May

George Morfogen as Don Dowd

Charles Blackwell as Speaker

Steve James as Dude

Jay Acovone as Plainclothes Cop

Alice Spivak as Magda

Calvin Ander as George

Peter Iacangelo as Plainclothes Cop

Michael Riney as Young D.J.

Louis Belero as Policeman #1

Gerald M. Kline as Policeman #2

Ben Slack as Hold-Up Man

Aaron Hurst as Beer Vendor

Sean Hurst as Beer Vendor

Peter Lopicolo as Shop Owner

Roger Camacho as T.V. Drop Kid

Steve Pabon as T.V. Drop Kid

Danielle Tiletnick as Daughter

Donna Sirota as Daughter's Friend

Tulane Howard II as Movie Theator Reactor

Karen Evans as Waitress

Rodi Alexander as Cigarette Girl

Ramón Franco as Sleez Bag Vendor #1

Riki Colon as Sleez Bag Vendor #2

Melanie Henderson as Renaissance Aide

Larry Silvestri as Cop on Marquee

Mandy Cameron as Beer Buyer

Paula Naples as Beer Buyer

Scott P. Sanders as Intern

Tiger Haynes as Andy

Cammi Lynn Buttner as Sleez Girl

Sarah Dougherty as Sleez Girl

Amy Gabriel as Sleez Girl

Sandra Lee Goga as Sleez Girl

Pamela Gotlin as Sleez Girl

Shuna Lydon as Sleez Girl

Kelly McClory as Sleez Girl

Marlena Seda as Sleez Girl

Marilyn Dobrin as Prostitute (uncredited)

Anibal O. Lleras as Cabby (uncredited)

Zoë Lund as Sleez Girl (uncredited)

Sharon Mitchell as Audience Member in Nightclub (uncredited)

Antone Pagán as Sleez Bag Vendor #3 (uncredited)

Ronda Swindell as Sleez Girl (uncredited)

Chelly Wilson as Woman at Ticket Booth (uncredited)