Michael Chiklis as John Belushi

Ray Sharkey as Angel Velasquez

J. T. Walsh as Bob Woodward

Patti D'Arbanville as Cathy Smith

Lucinda Jenney as Judy Belushi

Alex Rocco as Arnie Fromson

Gary Groomes as Dan Aykroyd

Jere Burns as Lou Connors

Clyde Kusatsu as Coroner Thomas Noguchi

Tom Bower as Detective

Earl Billings as Detective

Dakin Matthews as Washington Post Editor

J.C. Quinn as Comedy Coach

Blake Clark as Dusty Jenkins

Paul Ben-Victor as Tom Perino

Ned Bellamy as Paul Forrest