Elizabeth Taylor as Cleopatra

Richard Burton as Marcus Antonius

Rex Harrison as Julius Caesar

Pamela Brown as High Priestess

George Cole as Flavius

Hume Cronyn as Sosigenes

Cesare Danova as Apollodorus

Kenneth Haigh as Brutus

Andrew Keir as Agrippa

Martin Landau as Rufio

Roddy McDowall as Octavian - Caesar Augustus

Robert Stephens as Germanicus

Francesca Annis as Eiras

Grégoire Aslan as Pothinus

Martin Benson as Ramos

John Doucette as Achillas

Michael Hordern as Cicero

John Hoyt as Cassius

Carroll O'Connor as Casca

Andrew Faulds as Canidius

Michael Gwynn as Cimber

Peter Grant as Palace Guard (uncredited)

Marne Maitland as Euphranor

Richard O'Sullivan as Pharaoh Ptolemy XIII

Gwen Watford as Calpurnia

Douglas Wilmer as Decimus

Marie Devereux as Bacchanal Reveler

Herbert Berghof as Theodotos

Jacqueline Chan as Lotos

Isabel Cooley as Charmian

Mike Steen as Minor Role

Finlay Currie as Titus

Jean Marsh as Octavia

Meri Welles as Cleopatra's Handmaiden

Peter Forster as Officer

John Alderson as Roman Officer (uncredited)

John Alderton as 1st Officer (uncredited)

Jeremy Kemp as Agitator (uncredited)

Desmond Llewelyn as Senator (uncredited)

Jean Marsh as Octavia (uncredited)

Laurence Naismith as Arachesilaus (uncredited)

Larry Taylor as Roman Officer (uncredited)