Nia Vardalos as Fotoula "Toula" Portokalos

John Corbett as Ian Miller

Lainie Kazan as Maria Portokalos

Michael Constantine as Kostas "Gus" Portokalos

Andrea Martin as Aunt Voula

Joey Fatone as Angelo

Louis Mandylor as Nick Portokalos

Gia Carides as Nikki Portokalos

Christina Eleusiniotis as Toula Portokalos - Age 6

Marita Zouravlioff as Toula Portokalos - Age 12

Gerry Mendicino as Uncle Taki

Bess Meisler as Yiayia

Jayne Eastwood as Mrs. White

Fiona Reid as Harriet Miller

Bruce Gray as Rodney Miller

Frank Falcone as Suitor

Stavroula Logothettis as Athena

Ian Gomez as Mike

Petra Wildgoose as Car Pool Friend

John Kalangis as Greek Teacher

Kaylee Vieira as Schoolgirl

Melissa Todd as Car Pool Friend

Sarah Osman as Athena Portokalos - Age 15

Gale Garnett as Aunt Lexy