Will Smith as Muhammad Ali / Cassius Clay

Jamie Foxx as Drew 'Bundini' Brown

Jon Voight as Howard Cosell

Mario Van Peebles as Malcolm X

Ron Silver as Angelo Dundee

Jeffrey Wright as Howard Bingham

Mykelti Williamson as Don King

Jada Pinkett Smith as Sonji Roi

Nona Gaye as Belinda Ali

Michael Michele as Veronica Porche

Joe Morton as Chauncey Eskridge

Paul Rodríguez as Dr. Ferdie Pacheco

Bruce McGill as Bradley

Barry Shabaka Henley as Herbert Muhammad

Giancarlo Esposito as Cassius Clay, Sr.

Laurence Mason as Luis Sarria

LeVar Burton as Martin Luther King, Jr.

Albert Hall as Elijah Muhammad

David Cubitt as Robert Lipsyte

Ted Levine as Joe Smiley

Candy Ann Brown as Odessa

David Elliott as Sam Cooke

Shari Watson as Woman Singer

Malick Bowens as Joseph Mobutu

Michael Bentt as Sonny Liston

James Toney as 'Smokin' Joe Frazier

Alfred Cole as Ernie Terrell

Charles Shufford as George Foreman

Rufus Dorsey as Floyd Paterson

Robert Sale as Jerry Quarry

Vince Cooke as Jimmy Ellis

Damien 'Bolo' Wills as Ken Norton

David Haines as Rudy Clay / Rahaman Ali

Victoria Dillard as Betty Shabazz

Brad Greenquist as Marlin Thomas

Morgana Van Peebles as Malcolm X's Daughter

Maya Van Peebles as Malcolm X's Daughter

Maestro Harrell as Young Cassius Clay

William Utay as The Doctor

Kim Robillard as Jimmy Cannon

David Purdham as Madison Square Garden Announcer

Gailard Sartain as Gordon Davidson

Wade Williams as Lieutenant Jerome Claridge

Guy Van Swearingen as Induction FBI Man

Doug Hale as Judge Ingraham

LaDonna Tittle as Bundini's Landlady

Marc Grapey as Bob Arum

Herb Mitchell as Boxing Commissioner

Eddie Bo Smith Jr. as Malcolm's Bodyguard

Bobby Stuart as Thomas 15X Johnson

Patrick New as Room Service Guy

Ron O.J. Parson as Death Newsman

Ellis Williams as Family Photo Man

Alexandra Bokyun Chun as Asian Cosmetologist

John Gleeson Connolly as Assistant Director

Warner Saunders as Customer

Jack Reiss as Referee Arthur Mercante

Marty Denkin as Frazier Fight II Announcer

Tamara Lynch as Flight Attendant

Chico Benymon as Hampton House Announcer

Bill Plaschke as Miami Weigh-In Reporter

Steve Springer as Miami Weigh-In Reporter

Patrick M. Connolly as Announcer

Patrick C. Russell as Referee

Robert Byrd as Willie Reddick

Cedric Wills as Jersey Joe Walcott, Referee

Ronald A. DiNicola as Prosecutor

Moses Hollins as Man on Train

Daniel E. Gurevitz as Boxing Commission Reporter

Steven Randazzo as Reporter

Ray Bokhour as Reporter

Leonard Termo as Madison Square Garden Reporter

Johnny Ortiz as Madison Square Garden Reporter

Mark Salem as New York Reporter

Sheldon Fogel as New York Reporter

Jim Gray as New York Reporter

Melvin Thomas as Harlem Neighbor

Natalie Carter as Harlem Neighbor

Reginald Footman as Harlem Neighbor

Poe Poe as Harlem Reporter

Mel Dick as Louisville Sponsoring Group

Kim Taylor-Coleman as Lana Shabazz

Christian Stolte as Miami Cop

Vic Manni as Dressing Room Weigh-In Guy

Will Gill Jr. as Dick Sadler

Sylvaine Strike as ORTF Interviewer

Denis Luposo as Kinshasa Reporter

Sharon Wilkinson as Rose Jennings

Carol Hatchett as Pointer Sister

Judith Mwale as Pointer Sister

Keabetswe Motsilanyane as Pointer Sister

Richard Katanga as Mobutu Aide / Military Aide

Thomas Kariuki Matheri as Lieutenant Nsakala

Larry Hazzard Sr. as Zack Clayton

Derrick Brown as Larry Holmes

Rommel Hyacinth as The Pilot

Graham Hopkins as London Banker

Daniel Janks as CIA Man

Bradford E. Lang as Black Pilot

Michael Dorn as Black Pilot

Dan Robbertse as Reporter in Zaire

Graham Clarke as Reporter in Zaire

Dimitri Cassar as Reporter in Zaire

Frank Notaro as Reporter in Zaire

Mark Mulder as Reporter in Zaire

David W. Hess as Reporter in Zaire

Henrikennyo Mukenyi as Bula

Nathaniel Malekane as Archie Moore

Millard Arnold as Doc Broadus

Edda Collier as Blonde French Reporter

Yi Lu Wei as Chinese Delegate

Lee Cummings as Hunter Thompson

Zaa Nkweta as Foreman Fight Announcer

Themba Gasa as Idi Amin

Andrew P. Jones as Don King's Aide

Marc Kulazite Mboli as Additional Aide to Mobutu

Cimanga Kalambay as Additional Aide to Mobutu

Jean Bikoi as Additional Aide to Mobutu

James Gilbert as Sparring Partner in Africa

Carolina Lancaster as Dancer (uncredited)

Ron Madoff as Cameraman