Joe Lewis as Jonathan Cross / Jaguar

Christopher Lee as Adam Caine

Donald Pleasence as General Villanova

Barbara Bach as Anna Thompson

Capucine as Zina Vanacore

Joseph Wiseman as Ben Ashir

Woody Strode as Sensei

John Huston as Ralph Richards

Gabriel Melgar as Ahmed

Anthony De Longis as Bret Barrett

Sally Faulkner as Terry

Gail Grainger as Consuela

Anthony Heaton as Coblintz

Luis Prendes as Habish

Simón Andreu as Petrie

James Smillie as Reardon

Oscar James as Collins

Ray Jewers as Jessup

Ralph Orville Brown as Logan

Fedra Lorente as Angela

Silvia Aguilar as Zina's assistant

Steve Gerhardt as Adams

Jay T. Will as Kennedy

George Rigaud as French party guest (as Jorge Regaud)

Emilio Rodríguez as Italian party guest

Víctor Israel as Sicilian party guest

Maribel Hidalgo as Spanish party guest

Bill Currant as American party guest

Joseph Harrison as West Indian party guest

Taida Urruzola as Villanova's girl

Catherine Basseti as Richard's secretary

Law Chi-Chan as Willie

Yuen Wah as Hong Kong target (uncredited)