Jennifer Lopez as Catherine Deane

Vince Vaughn as Peter Novak

Vincent D'Onofrio as Carl Rudolph Stargher

Catherine Sutherland as Anne Marie Vicksey

James Gammon as Teddy Lee

Colton James as Edward Baines

Dylan Baker as Henry West

Marianne Jean-Baptiste as Dr. Miriam Kent

Gerry Becker as Dr. Barry Cooperman

Musetta Vander as Ella Baines

Patrick Bauchau as Lucien Baines

Jake Weber as Gordon Ramsey

Dean Norris as Cole

Tara Subkoff as Julia Hickson

Lauri Johnson as Mrs. Hickson

John Cothran as Agent Stockwell

Jack Conley as Agent Brock

Kamar de los Reyes as Officer Alexander

Pruitt Taylor Vince as Dr. Reid

Peter Sarsgaard as Julia Hickson's Fiancee (uncredited)

Christopher Janney as Swat Team Member

Nicholas Cascone as FBI Technician

Joe La Piana as FBI K-9 Agent

Jake Thomas as Young Carl Stargher

Kim Chizevsky-Nicholls as Stargher's Victim

Jennifer Day as Stargher's Victim

Alanna Vicente as Stargher's Victim

Aja Echols as Stargher's Victim

Vanessa Branch as Stargher's Victim

Elena Maddalo as Stargher's Victim

Gareth Williams as Stargher's Father

Monica Lacy as Mother

Joy Creel as Mother

Leanna Creel as Mother

Alan D. Purwin as Helicopter Pilot