Sean Astin as Mikey Walsh

Josh Brolin as Brand Walsh

Jeff Cohen as Lawrence "Chunk" Cohen

Corey Feldman as Clark "Mouth" Devereaux

Kerri Green as Andy Carmichael

Martha Plimpton as Stephanie "Stef" Steinbrenner

Ke Huy Quan as Richard "Data" Wang

John Matuszak as Sloth

Robert Davi as Jake Fratelli

Joe Pantoliano as Francis Fratelli

Anne Ramsey as Mama Fratelli

Lupe Ontiveros as Rosalita

Mary Ellen Trainor as Mrs. Walsh

Keith Walker as Mr. Walsh

Steve Antin as Troy

Paul Tuerpe as Sheriff

George Robotham as Prison Guard

Charles McDaniel as Chunk's Father

Elaine Cohen McMahon as Chunk's Mother

Michael Paul Chan as Data's Father

George Nicholas McLean as Mouth's Father

Bill Bradley as Bill

Jeb Stuart Adams as Troy's Friend #1

Eric Briant Wells as Troy's Friend #2

Gene Ross as Man in Shower #1

Max Segar as Man in Shower #2

Newt Arnold as Man in Shower #3

Jack O'Leary as Reporter #1

Patrick Cameron as Reporter #2

Orwin C. Harvey as Tennis Player

Ted Grossman as FBI Man

Richard Donner as Policeman (uncredited)

Eydie Faye as Eydie - Chunk's Older Sister (uncredited)

Rick Kuhn as Parent #3 (uncredited)

Cyndi Lauper as Cyndi Lauper (archive footage)

Jennie Lew Tugend as Mrs. Wang (uncredited)

Lisa Quan as Data's Sister (uncredited)

Curt Hanson as Mr. Perkins (as Curtis Hanson)