Sean Astin as Mikey

Josh Brolin as Brand

Jeff Cohen as Chunk

Corey Feldman as Mouth

Kerri Green as Andy

Martha Plimpton as Stef

Ke Huy Quan as Data

John Matuszak as Sloth

Robert Davi as Jake

Joe Pantoliano as Francis

Anne Ramsey as Mama Fratelli

Lupe Ontiveros as Rosalita

Mary Ellen Trainor as Mrs. Walsh

Keith Walker as Mr. Walsh

Curt Hanson as Mr. Perkins

Steve Antin as Troy

Paul Tuerpe as Sheriff

George Robotham as Prison Guard

Charles McDaniel as Chunk's Father

Elaine Cohen McMahon as Chunk's Mother

Michael Paul Chan as Data's Father

Nick McLean as Mouth's Father

Bill Bradley as Bill

Jeb Stuart Adams as Troy's Friend #1

Eric Briant Wells as Troy's Friend #2

Gene Ross as Man in Shower #1

Max Segar as Man in Shower #2

Newt Arnold as Man in Shower #3

Jack O'Leary as Reporter #1

Patrick Cameron as Reporter #2

Orwin C. Harvey as Tennis Player

Ted Grossman as FBI Man

Richard Donner as Policeman (uncredited)

Eydie Faye as Chunk's Sister (uncredited)

Rick Kuhn as Parent (uncredited)

Jennie Lew Tugend as Data's Mother (uncredited)

Lisa Quan as Data's Sister (uncredited)

Keenan Wynn as Chester Copperpot (uncredited)