Steve Oedekerk as Loke Groundrunner / Dad / Jake / 'We've Been Hit' (voice)

Mary Jo Keenen as Geranium / Old Geranium (voice)

Paul Greenberg as Prissypeo / The Captain / 'Lovely Ship' Steward (voice)

Rob Paulsen as Oobedoob Benubi / Mr. Prickle / Thumbtrooper (voice)

Jim Jackman as Dentist / Boiler Room Guy #1 / Crunchy / Lieutenant (voice)

Mark DeCarlo as Black Helmet Man / The Interviewer / TV Anchor (voice)

Jim Hope as Commander Cuticle / Effeminate Thumb / Instructor (voice)

David Floyd as Baldie the Thumb Wrestler / Uncle Soondead / Fighter (voice)

Megan Cavanagh as Fighter Pilot #2 / Geranium's Servant (voice)

Ross Shafer as Hand Duet (voice) (as Ross Schaefer)

Andrea Fears as Princess Bunhead (voice)

Matthew Aufdenspring as We're Sinking! (voice)

Mary Mares as No We Can't Be Sinking (voice)

John Laus as Baby Buyer / Piano Man (voice)

Tim Tarkinan as It's a Big Ship (voice)

Heidi Fugeman as Ship Must go on for Miles (voice)

Joe Liss as It's a Big Ship!' / Bedwetter / 'I Wet Myself (voice)

Jenny Rose as What a Lovely Big Ship!' / 'We're Going Down! (voice)

Eric Trueheart as All Aboard Steward / Good Gravy What a Ship! (voice)

Tony Pyle as Submarine Pilot / Excited One-Eyed Thumb / Lookout #3 (voice)