Vino G. Bastian as Buya Hamka

Laudya Cynthia Bella as Siti Raham

Donny Damara as Haji Rasul

Desy Ratnasari as Ummi Safiah

Marthino Lio as Amir

Anjasmara as Soekarno

Verdi Solaiman as Abdul Karim/ Oei Tjeng Hien

Bima Azriel as Rusydi (young)

Zayyan Sakha as Zaki (young)

Mawar Eva De Jongh as Kulsum

Mellya Baskarani as Aminah

Yoriko Angeline as Ola

Novita Hardini as Fatimah

Wafda Saifan Lubis as Rozak

Yoga Pratama as Zaki

Roy Sungkono as Rusydi

Ajil Ditto as Fakhri

Alfie Alfandy as Dadang

Donny Kesuma as Ayah Kulsum

Ade Firman Hakim as Karta

Ben Kasyafani as Zainuddin Labai

Ferry Salim as Gubernur Nakashima

Carmela van der Kruk as Dutch Army Commander

Rasyid Albuqhory as Rusydi Hamka

Raditya Albuqhari as Zaki Hamka

Ivan Leonardy as Ayah Ola

Sulistyo Kusumawati as Ibu Ola