Ralph Fiennes as Lawrence

Stanley Tucci as Bellini

John Lithgow as Tremblay

Isabella Rossellini as Sister Agnes

Lucian Msamati as Adeyemi

Carlos Diehz as Benitez

Sergio Castellitto as Tedesco

Brían F. O'Byrne as O'Malley

Merab Ninidze as Sabbadin

Thomas Loibl as Mandorff

Jacek Koman as Wozniak

Bruno Novelli as Dead Pope

Rony Kramer as Mendoza

Valerio Da Silva as Father Haas

Joseph Mydell as Nakitanda

Vincenzo Failla as Guttoso

Garrick Hagon as Krasinski

Madhav Sharma as Landolfi

Loris Loddi as Villanueva

Roberto Citran as Lombardi

Antonio Toma as Jr. Cardinal-Deacon Guerrini

Balkissa Souley Maiga as Sister Shanumi

Romuald Kłos as Brotzkus

Willie Jonah as Lowenstein