Kiefer Sutherland as Samson (voice)

Jim Belushi as Benny (voice)

Eddie Izzard as Nigel (voice)

Janeane Garofalo as Bridget (voice)

William Shatner as Kazar (voice)

Richard Kind as Larry (voice)

Greg Cipes as Ryan (voice)

Colin Hay as Fergus Flamingo (voice)

Miles Marsico as Duke (voice)

Jack De Sena as Eze (voice)

Don Cherry as Penguin MC (voice)

Christian Argueta as Hamir (voice)

David Cowgill as Hamir (voice)

Lenny Venito as Stan (voice)

Joseph Siravo as Carmine (voice)

Colin Cunningham as Hyrax (voice)

Patrick Warburton as Blag (voice)

Jonathan Kimmel as Scab (voice)

Eddie Gossling as Scraw (voice)

Miss Coco Peru as Mama Hippo (voice)

Jason Harris as Additional Voices (voice)

Kevin Michael Richardson as Samson' Father (voice)

Jess Harnell as Additional Voices (voice)

Fred Tatasciore as Additional Voices (voice)

Laraine Newman as Additional Voices (voice)

Kari Wahlgren as Baby Hippo/Walla (voice)

Steve Williams as Additional Voices (voice)

Hannah Williams as Additional Voice (voice)

Audrey Wasilewski as Additional Voice (voice)

Peter Pamela Rose as Additional Voice (voice)

Paul Pape as Man #1 (voice)

Nolan North as Additional Voices (voice)

Mona Marshall as Screaming Woman / Dung Beetle #4 (voice)

Danny Mann as Additional Voices (voice)

Carolyn Lawrence as Ladybird / Monkey Girl (voice)

Josh Keaton as Rhino (voice)

Daniel Kaz as Additional Voices (voice)

John Kassir as Additional Voice (voice)

Emily Johnson as (voice)

Bridget Hoffman as (voice)

Nicholas Guest as (voice)

Eddie Frierson as (voice)

Pat Fraley as (voice)

Jeannie Elias as (voice)

Terri Douglas as Koala Toy (voice)

Debi Derryberry as Dung Beetle #3 / Monkey Girl (voice)

Jason Connery as Flamingo (voice)

Bob Bergen as Additional Voices (voice)

Greg Berg as Vulture (voice)

Keith Anthony as (voice)

Bob Joles as Camo / Ringleader (voice)

Chris Edgerly as Cloak (voice)

Julianne Buescher as Dung Beetle #2 (voice)

Nika Futterman as Dung Beetle #1 (voice)

Dominic Scott Kay as Young Samson (voice)