Justin Roiland as Leroy Peloni (voice)

Zach Hadel as Reggie Paloni (voice)

Pamela Adlon as Cheruce Paloni (voice)

Vatche Panos as Little Long Legs (voice)

Kari Wahlgren as Aunt Stephanie (voice)

Steve Agee as

Ryder Bird as

Lombardo Boyar as

Emma Chamberlain as Megg (voice)

Macaulay Culkin as Mogg (voice)

Dave Foley as Owl (voice)

Jon Glaser as Werewolf Jones (voice)

Dawn Cody as Bronwen (voice)

Eugene Cordero as Banana Guy

Michael Cusack as Nugget (voice)

Olivia DeLaurentis as Annie Alphabet

Drew Droege as

Robert Englund as

David Firth as Mr. Clack / Jason / Guest (Slaughter Cafe)

Kate Freund as ZAP

Molly Garcia as

Ian Gary as

Gilbert Gottfried as Reed

Zach Hadel as

Jacob Hair as

Lee Hardcastle as

Jordan Harris as

Joel Haver as

Sydney Heller as

Echo Kellum as

Tom Kenny as

Matthew Lillard as Chip (Slashtronaut) (voice)

Michelle Nunn as Black Chick

Vatche Panos as

Karl Withakay Parish as

Ryan Ridley as

Al Rodrigo as

Jaime Rodríguez as

Paul Scheer as Leon (Banana Party) / Tenant (The Dreston) (voice)

Rob Schrab as

Peter Serafinowicz as

Carla Simpson as

Tara Strong as

Mariah Tavares as

David Tennant as Roach Chef (voice)

Brian Wysol as Zombie (The Dreston) (voice)

Trent Lenkarski as

Patti Harrison as Megg (voice), online only version