Tate Donovan as Hercules (voice)

Josh Keaton as Young Hercules (voice)

Roger Bart as Young Hercules (singing voice)

Danny DeVito as Philoctetes (voice)

James Woods as Hades (voice)

Susan Egan as Meg (voice)

Bobcat Goldthwait as Pain (voice)

Matt Frewer as Panic (voice)

Rip Torn as Zeus (voice)

Samantha Eggar as Hera (voice)

Barbara Barrie as Alcmene (voice)

Hal Holbrook as Amphitryon (voice)

Paul Shaffer as Hermes (voice)

Amanda Plummer as Clotho (voice)

Carole Shelley as Lachesis (voice)

Paddi Edwards as Atropos (voice)

Charlton Heston as Narrator (voice)

Lillias White as Calliope the Muse of Epics (voice)

Cheryl Freeman as Melpomene the Muse of Tragedy (voice)

LaChanze as Terpsichore the Muse of Dance (voice)

Roz Ryan as Thalia the Muse of Comedy (voice)

Jim Cummings as Nessus the River Centaur / Tall Thebian / Elderly Thebian (voice)

Keith David as Apollo the Sun God (voice)

Wayne Knight as Demetrius the Pot Maker (voice)

Sherry Lynn as Additional Voices (voice)

Mickie McGowan as Additional Voices (voice)

Jack Angel as Additional Voices (voice)

Debi Derryberry as Additional Voices (voice)

Patrick Pinney as Cyclops (voice)

Corey Burton as Burnt Man (voice)

Mary Kay Bergman as Earthquake Lady (voice)

Kathleen Freeman as Heavyset Woman (voice)