Edmund Lowe as Philo Vance

Virginia Bruce as Zalia Graem

Benita Hume as Nurse Gladys Beeton

Douglas Walton as Floyd Garden

Nat Pendleton as Sergeant Ernest Heath

Gene Lockhart as Edgar Lowe Hammle

H.B. Warner as Major Fenwicke-Ralston

Kent Smith as Woode Swift

Grant Mitchell as District Attorney Markham

Frieda Inescort as Mrs. Madge Fenwicke-Ralston

Henry B. Walthall as Dr. Garden

Jessie Ralph as Mrs. Hammle

Charles Trowbridge as Inspector Colby

Etienne Girardot as Dr. Doremus

William Austin as Sneed, Hammle's Butler (Uncredited)

Don Brodie as Messenger (Uncredited)

Olaf Hytten as Vance's Butler (Uncredited)

Rosalind Ivan as Mrs. Jepson (Uncredited)

Fred Kelsey as Heath's Assistant (Uncredited)

Wilbur Mack as Man Yelling at Race Track (Uncredited)

Lee Phelps as Bus Driver (Uncredited)

Alexander Pollard as Waiter at Race Track (Uncredited)

Jack Roper as Servant Eating Caviar (Uncredited)

Matty Roubert as Newsboy (Uncredited)

Dorothy Vernon as Woman Running for Bus (Uncredited)

Duke York as Traffic Cop (Uncredited)