Jon Heder as Jeffrey Mannus

Diane Keaton as Jan Mannus

Jeff Daniels as Mert Rosenbloom

Anna Faris as Nora Flannigan

Eli Wallach as Seymour Warburton

Dorian Missick as Mitch

Sarah Chalke as Maya

Mary Kay Place as Barbara

Adam Devine as Alhorn

Simon Helberg as Rathkon

Jenny Ladner as Alison

Ben Crowley as Skater Punk

Laura Kightlinger as Mert's Secretary

Jessie Graff as Wrestler

Jonah Ray Rodrigues as Ogre

Evan Peters as Keith