William Powell as Nick Charles

Myrna Loy as Nora Charles

Virginia Grey as Lois MacFay

Otto Kruger as Van Slack

C. Aubrey Smith as Burr MacFay

Ruth Hussey as Dorothy Waters

Nat Pendleton as John Guild

Patric Knowles as Dudley Horn

Tom Neal as Freddie Coleman

Phyllis Gordon as Isabella Bellam

Sheldon Leonard as Phil Church

Don Costello as "Diamond Back" Vogel

Harry Bellaver as "Creeps" Binder

William A. Poulsen as Nickie Charles

Muriel Hutchison as Culverton "Smitty" Smith

Abner Biberman as 'Dum-Dum'

Skippy as Asta

Doodles Weaver as Gatekeeper (uncredited)

Shemp Howard as Wacky (uncredited)

Marjorie Main as Mrs. Dolley (uncredited)

Murray Alper as Larry (uncredited)

Sandra Andreva as Woman With Nick in Cafe (uncredited)

William Bailey as Freight Elevator Operator (uncredited)

Roy Barcroft as Slim (uncredited)

Brooks Benedict as West Indies Club Patron (uncredited)

James Blaine as Policeman (uncredited)

Charles Brokaw as State Trooper (uncredited)

Paul E. Burns as Ticket Agent (uncredited)

Eddie Buzard as Newsboy (uncredited)

Anita Camargo as Hat Check Girl (uncredited)

Jack Rube Clifford as Policeman (uncredited)

Frank Coletti as State Trooper (uncredited)

Gino Corrado as West Indies Club Patron (uncredited)

Nell Craig as Nursemaid #1 (uncredited)

Carmen D'Antonio as Specialty Dancer (uncredited)

Joe Devlin as Barney (uncredited)

Joe Downing as Hoodlum (uncredited)

Ralph Dunn as Baggage Man (uncredited)

Dick Elliott as Detective (uncredited)

Matty Fain as Hoodlum (uncredited)

Walter Fenner as Detective (uncredited)

Miguel Fernández Mila as Specialty Dancer (uncredited)

Jack Gardner as Driver (uncredited)

Edward Gargan as Detective Quinn (uncredited)

Martín Garralaga as Pedro (uncredited)

Eddie Gribbon as Baggage Man (uncredited)

Rosemary Grimes as Woman With Nick in Cafe (uncredited)

George Guhl as Second Gate Guard (uncredited)

James Guilfoyle as Jake (uncredited)

Eddie Hall as Baggage Man #2 (uncredited)

Edward Hearn as Detective (uncredited)

Thomas E. Jackson as Detective (uncredited)

Gladden James as Fingerprint Man (uncredited)

Milton Kibbee as Detective (uncredited)

Toni LaRue as Woman With Nick in Cafe (uncredited)

George Lloyd as West Indies Club Patron (uncredited)

Alphonse Martell as West Indies Club Waiter (uncredited)

Thomas Martin as Spectator in Alley (uncredited)

Pat McKee as Father (uncredited)

Horace McMahon as MacFay's Chauffeur (uncredited)

Rudolph Medina as Specialty Dancer (uncredited)

Tina Menard as Woman With Nick in Cafe (uncredited)

Harold Miller as West Indies Club Patron (uncredited)

Howard M. Mitchell as Policeman (uncredited)

Frank Moran as Butch (uncredited)

Alberto Morin as West Indies Club Waiter (uncredited)

Philip Morris as Baggage Man (uncredited)

Paul Newlan as Tom (uncredited)

Nellie V. Nichols as Raphael's Mother (uncredited)

William Pagan as Policeman (uncredited)

Nestor Paiva as West Indies Club Headwaiter (uncredited)

Eddie Parker as State Trooper (uncredited)

Milton Parsons as Coroner (uncredited)

Guy Repp as Waiter #1 (uncredited)

Bert Roach as Cookie (uncredited)

Claire Rochelle as Telephone Operator (uncredited)

Constantine Romanoff as Tall Father in Derby (uncredited)

Ronald R. Rondell as West Indies Club Patron (uncredited)

Ramon Ros as Specialty Dancer (uncredited)

Charles Sherlock as Police Photographer (uncredited)

Lee Shumway as Policeman (uncredited)

Rafael Alcayde as Gigolo (uncredited)

Frank Sully as Pete (uncredited)

William Tannen as State Trooper (uncredited)

Stanley Taylor as Taxi Driver (uncredited)

Fred Velasco as Specialty Dancer (uncredited)

Blanca Vischer as Woman With Nick in Cafe (uncredited)

Richard Calderon as Raphael - Wacky's Baby (uncredited)

Dick Gordon as West Indies Club Patron (uncredited)