Ewan McGregor as Lincoln Six Echo / Tom Lincoln

Scarlett Johansson as Jordan Two Delta / Sarah Jordan

Djimon Hounsou as Albert Laurent

Sean Bean as Dr. Bernard Merrick

Steve Buscemi as James 'Mac' McCord

Michael Clarke Duncan as Starkweather Two Delta / Jamal Starkweather

Ethan Phillips as Jones Three Echo

Brian Stepanek as Gandu Three Echo

Noa Tishby as Community Announcer

Siobhan Flynn as Lima One Alpha

Troy Blendell as Laurent Team Member

Jamie McBride as Laurent Team Member

Kevin McCorkle as Laurent Team Member

Gary Nickens as Laurent Team Member

Kathleen Rose Perkins as Laurent Team Member

Katy Boyer as Harvest Surgeon

Wendy Haines as Harvest Nurse

Glenn Morshower as Medical Courier

Shawnee Smith as Suzie

Max Baker as Chief of Incubation

Phil Abrams as Obgyn

Svetlana Efremova as Midwife

Randy Oglesby as Harvest Surgeon

Yvette Nicole Brown as Harvest Nurse

Taylor Gilbert as Harvest Nurse

Tim Halligan as Institute Coroner

Michael Canavan as Extraction Room Doctor

Jimmy Smagula as Extraction Room Technician

Ben Tolpin as Extraction Room Technician

Rich Hutchman as Dept. of Operations Supervisor

Gonzalo Menendez as Dept. of Operations Technician

Olivia Tracey as Dept. of Operations Agnate

Ray Xifo as Elevator Agnate

Mary Pat Gleason as Nutrition Clerk

Whitney Dylan as Client Services Operator

Mitzi Martin as Atrium Tour Guide

Shelby Leverington as Tour Group Woman

Don Creech as God-Like Man

Richard V. Licata as Board Member

Chris Ellis as Aces & Spades Barman

Eric Stonestreet as Ed the Trucker

Kenneth Hughes as Censor

Richard Whiten as Laurent Team Member

Robert Sherman as Agnate in Pod

Ashley Yegan as Stim Bar Bartender

Lewis Dauber as Tour Group Man

Eamon Behrens as Censor

Alex Carter as Censor

Kevin Daniels as Censor

Grant Garrison as Censor

Brian Leckner as Censor

Dakota Mitchell as Censor

Martin Papazian as Censor

Phil Somerville as Censor

Ryan Tasz as Censor

Kirk Ward as Censor

Kelvin Han Yee as Censor

Don Michael Paul as Bar Guy

James Granoff as Sarah's Son

James Hart as LAPD Officer

Trent Ford as Calvin Klein Model

Thomas Ely Sage as Girl at Beach

Jake Soldera as Little Boy in Line

Mark Christopher Lawrence as Construction Worker

Matt McColm as Cop (uncredited)

Kim Coates as Charles Whitman (uncredited)

Richard John Walters as Agnate (uncredited)