Roger Carel as Astérix (voice)

Alexandre Astier as Le centurion Oursenplus (voice)

Lionnel Astier as Cétautomatix (voice)

Serge Papagalli as Abraracourcix (voice)

François Morel as Ordralfabétix (voice)

Élie Semoun as Cubitus (voice)

Guillaume Briat as Obélix (voice)

Lorànt Deutsch as Anglaigus (voice)

Alain Chabat as Senator Prospectus (voice)

Géraldine Nakache as Dulcia (voice)

Florence Foresti as Bonemine (voice)

Laurent Lafitte as Duplicatha (voice)

Brice Fournier as Sénateur Pesticius / Citoyen / Brute romaine (voice)

Pascal Demolon as Cordius (voice)

Philippe Morier-Genoud as Jules César (voice)

Joëlle Sevilla as lélosubmarine / Matrone (voice)

Olivier Saladin as Sénateur Samus (voice)

Damien Gillard as Médius / Brute romaine / Romain (voice)

Benjamin Gauthier as Médecin / Le guide / Romain (voice)

Virginia Anderson as Romaine / Matrone (voice)

Pascal Demolon as Gladiateur (Goth) (voice)

Baptiste Lecaplain as Gladiateur (Numide) (voice)

Pauline Moingeon Vallès as Romaine (voice) (as Pauline Moingeon)

Julien Meunier as Voix additionnelles (voice)

Martial Le Minoux as Voix additionnelles (voice)

Vincent Ropion as Voix additionnelles (voice)

Christian Peythieu as Voix additionnelles (voice)

Jérémy Bardeau as Voix additionnelles (voice)

François Raison as Voix additionnelles (voice)

Matthieu Albertini as Voix additionnelles (voice)

Hervé Grull as Voix additionnelles (voice)

Juan Llorca as Voix additionnelles (voice)

Antoine Lelandais as Voix additionnelles (voice)

Magali Rosenzweig as Voix additionnelles (voice)

Céline Melloul as Voix additionnelles (voice)

Marie-Madeleine Burguet as Voix additionnelles (voice)

Delphine Braillon as Voix additionnelles (voice)

Axelle Bossard as Voix additionnelles (voice)

Brigitte Guedj as Voix additionnelles (voice)

Brigitte Lecordier as Voix additionnelles (voice)

Aurélie Valat as Voix additionnelles (voice)

Jean-Claude Donda as Voix additionnelles (voice)