Ben Stiller as Larry Daley / Laaa

Robin Williams as Theodore Roosevelt

Owen Wilson as Jedediah Smith

Steve Coogan as Octavius

Ricky Gervais as Dr. McPhee

Dan Stevens as Sir Lancelot

Rebel Wilson as Tilly

Skyler Gisondo as Nick Daley

Rami Malek as Ahkmenrah

Patrick Gallagher as Attila the Hun

Mizuo Peck as Sacajawea

Ben Kingsley as Merenkahre

Dick Van Dyke as Cecil

Mickey Rooney as Gus

Bill Cobbs as Reginald

Andrea Martin as Rose

Rachael Harris as Madeline Phelps

Matt Frewer as Archibald Stanley

Brad Garrett as Easter Island Head (voice)

Regina Taufen as New York Reporter (voice)

Percy Hynes White as C.J. Fredericks

Brennan Elliott as Robert Fredericks

Kerry van der Griend as Neanderthal #1

Matthew Harrison as Neanderthal #2

Jody Racicot as Neanderthal #3

Randy Lee as Hun #1

Darryl Quon as Hun #2

Paul Cheng as Hun #3

Gerald Wong as Hun #4

Anjali Jay as Shepseheret

Matty Finochio as Roman Sentry

Patrick Sabongui as Amir

Amir M. Korangy as 1938 Egyptian Worker

Louriza Tronco as Andrea

Sophie Levy as Sophie

Jin Sangha as Egyptian High Priest

James Neate as Augustus Statue

Alice Eve as Alice Eve (uncredited)

Hugh Jackman as Hugh Jackman (uncredited)

Kishore Bhatt as Theatre Patron (uncredited)

Dmitrious Bistrevsky as Greek Statue (uncredited)

Hannah Blamires as Theatre Patron (uncredited)

Jill Buchanan as Passerby (uncredited)

Arpit Chaudhary as Theatre Patron (uncredited)

Michael Denis as Young Ahkmenrah's Father (uncredited)

Theo Devaney as Lord Nelson (uncredited)

John Dryden as Mummy (uncredited)

Jordan Gardiner as Wealthy Donor (uncredited)

Ian Hawes as Gala Photographer (uncredited)

Nils Hognestad as Cowboy (uncredited)

Tony Honickberg as Theatre Patron (uncredited)

Todor Jordanov as Museum Guard (uncredited)

Zivile Kaminskaite as Gala Event Wealthy Donor (uncredited)

Shaun Lucas as Museum Patron / Passerby (uncredited)

Sid Man as Passerby (uncredited)

Craig March as NY Cop (uncredited)

Stuart Matthews as Theatre Patron (uncredited)

Martyn Mayger as Action Car Driver (uncredited)

Doris McCarthy as Wealthy Donor (uncredited)

Pete Meads as Passerby (uncredited)

Leah Perkins as BMW Driver (uncredited)

Jacqueline Ryan as Wealthy Donor (uncredited)

Andrea Sandell as Passerby (uncredited)

Steve Saunders as Passerby (uncredited)

Bomber Hurley Smith as Roman Sentry (uncredited)

Celeste White Steele as Theater Attendee (uncredited)

Ella Stiller as Child on London Bus (uncredited)

Quinn Dempsey Stiller as Child on London Bus (uncredited)

Winson Ting as Man (uncredited)

Stefano Villabona as Gala Photographer (uncredited)

Seth Whittaker as Museum Guard (uncredited)

Buppha Witt as Passerby (uncredited)

Brian Woodward as Theatre Patron (uncredited)

Crystal the Monkey as Dexter