Keanu Reeves as Alex Wyler

Sandra Bullock as Kate Forster

Christopher Plummer as Simon Wyler

Ebon Moss-Bachrach as Henry Wyler

Willeke van Ammelrooy as Kate's Mother

Dylan Walsh as Morgan

Shohreh Aghdashloo as Anna Klyczynski

Lynn Collins as Mona

Mike Bacarella as Mulhern

Kevin M. Brennan as Waiter

Frank Caeti as Cove Patron

Aliyah Carr as Girl Patient

Jennifer Clark as Nurse Practitioner

Jacob D. Dumelle as Patient on Gurney

Scott Elias as Doug

Lori Ann Gerdisch as I.C.U. Nurse

Cynthia Kaye McWilliams as Vanessa Vanderbeck

India Neilan as Hostess

Mia Park as Receptionist

Jacqueline Williams as Madhvi Patel

Peggy Roeder as Attendant

Jason Wells as Costello

Tiffini Funches as Young Nurse

Jennifer Kern as Nurse

Michael Andrew Gorman as Cove Bartender