Nicolas Cage as Seth

Meg Ryan as Maggie Rice

Andre Braugher as Cassiel

Dennis Franz as Nathaniel Messinger

Colm Feore as Jordan

Robin Bartlett as Anne

Joanna Merlin as Teresa Messinger

Sarah Dampf as Susan

Nigel Gibbs as Doctor

John Putch as Man in Car

Lauri Johnson as Woman in Car

Christian Aubert as Foreign Visitor in Car

Rhonda Dotson as Susan's Mother

Jay Patterson as Air Traffic Controller

Shishir Kurup as Jimmy, Anesthesiologist

Brian Markinson as Tom, Surgical Fellow

Elisabeth Shue as Pregnant Woman

Alexander Gould as Little Boy (Uncredited)

Kieu Chinh as Asian Woman

Nick Offerman as Construction Worker

Kim Murphy as Balford's Daughter