Jeff Goldblum as Nick Deezy

Cyndi Lauper as Sylvia Pickel

Peter Falk as Harry Buscafusco

Googy Gress as Ingo Swedlin

Julian Sands as Dr. Harrison Steele

Darryl Henriques as Ricardo

Ramon Bieri as Eli Diamond

Michael Lerner as Burt Wilder

Leo V. Finnie III as Monty Man

Rodney Kageyama as Dr. Harmon

Van Dyke Parks as Dr. Weiner

Hercules Vilchez as Juan

Jerry Vichi as Baseball Man

Ray Stoddard as Dr. Scott

Harvey J. Goldenberg as Lyle

Tom Henschel as Dr. Drake

Susan Bugg as Dr. Silver

Steve Buscemi as Fred

Joseph V. Perry as Dave

Park Overall as Jane

Max Perlich as Busboy

John Kapelos as Eugene

Bruce MacVittie as Tony

Don Bexley as Lou

Bill McCutcheon as Mr. Van Der Meer

Jennifer Balgobin as Gloria

Karen Akers as Hillary

Fernando Verdugo as Bellhop

Ronald G. Joseph as Carl

Aharon Ipalé as Alejandro De La Vivar

Elizabeth Peña as Consuelo

Robert Covarrubias as Waiter

Elvira De Val as Nurse

Ronald Paul Ramirez as Hotel Clerk