Dwayne Johnson as Derek Thompson / Tooth Fairy

Stephen Merchant as Tracy

Ashley Judd as Carly

Julie Andrews as Lily

Ryan Sheckler as Mick Donnelly

Seth MacFarlane as Ziggy

Destiny Whitlock as Tess

Chase Ellison as Randy

Darien Provost as Gabe

Alex Ferris as Shelter Cove Kid

Nicole Muñoz as Kelly

Brendan Meyer as Ben

Josh Emerson as Kyle

Brandon T. Jackson as Duke

Dan Joffre as Tooth Fairy #1

Ellie Harvie as Permit Woman

Barclay Hope as Coach

Michael Daingerfield as Announcer

Dale Wolfe as Color Commentator

Anthony Bewlz as Brad

Brendan Penny as Josh

Lee Tichon as Andreas

Jill Morrison as Shelter Cove Mom

Rukiya Bernard as Amnesia Woman

Maya Washington as Amnesia Daughter

Daniel Bacon as Fan

Christina Schild as Poltergeist Woman

Nicholas Carella as Poltergeist Man

Derek Gilroy as Crazed Fan

Brendan Beiser as Teddy's Dad

Fiona Hogan as Scared Woman

Peter Kelamis as Talent Show Teacher

Steve Levy as Himself

Candus Churchill as Amnesia Grandma

David Quinlan as Gabe's Dad

John Tench as Inmate

Ron Toffolo as Sports Reporter

Stephen Holmes as Shelter Cove Dad

Billy Crystal as Jerry (uncredited)