John Cusack as Adam

Craig Robinson as Nick

Rob Corddry as Lou

Clark Duke as Jacob

Sebastian Stan as Blaine

Crispin Glover as Phil

Lyndsy Fonseca as Jennie

Lizzy Caplan as April

Collette Wolfe as Kelly

William Zabka as Rick

Chevy Chase as Repairman

Charlie McDermott as Chaz

Aliu Oyofo as Young Nick

Jake Rose as Young Adam

Brook Bennett as Young Lou

Yan-Kay Crystal Lowe as Zoe

Jessica Paré as Tara

Kellee Stewart as Courtney

Julia Maxwell as Lucy

Geoff Gustafson as Dr. Jeff

Austin Warren as Nick's Band Member

Adam Sabla as Nick's Band Member

Jocelyn C. Waugh as Nick's Band Member

Curtis Santiago as Nick's Band Member

Ryan Guldemond as Nick's Band Member

Jeremy Page as Nick's Band Member

Anthony Dallas as Nick's Band Member

Odessa Rojen as Young Courtney

Viv Leacock as Courtney's Dad

Jamie Switch as Massive Cell Phone Guy

Chad Garner as "Poison" Tribute Band - Unskinny Bop

Donald MacDonald as "Poison" Tribute Band - Unskinny Bop

Chad MacDonald as "Poison" Tribute Band - Unskinny Bop

Anthony Pagni as "Poison" Tribute Band - Unskinny Bop

Blaine Anderson as MC

Michael Roberds as Manager

Daren A. Herbert as Receptionist

Megan Holmes as 'Where's the Beef' Girl

Ecstasia Sanders as Girl at Club

Eddie Ruttle as Beer Luge Guy

Heathcliffe Scaddan as Beer Luge Guy

Peter Wilson as Beer Luge Guy

Brent Lister as Blaine's Crony

Lars Anderson as Blaine's Crony

Paul Dzenkiw as Blaine's Crony

Rhys Williams as Blaine's Crony

Amy Esterle as Hot Tub Girl

Natalia Dawn as Hot Tub Girl

Ava Leemet as Candy Girl

Willy Lavendel as Fancy Ski Guy

Crystal Tisiga as Fancy Ski Girl

Marie West as Winterfest Bartender

Josh Heald as Manager

Lynda Boyd as Adam's Secretary (uncredited)

Jacob Blair as Gunnar (uncredited)

Rob LaBelle as Stewart (uncredited)

Robert Wu as Mr. Wang (uncredited)

Thomas Lennon as Customer (uncredited)

Diora Baird as Rick's Wife (uncredited)

Luke Ryan as Hot Tub Bear (uncredited)

Eli Jane as Hot Tub Girl (uncredited)

Amber Hay as Vince Neil's Video Girl (uncredited)

Cole Carson as Guy in Kodiak Restroom (uncredited)

Keith Roenke as Kodiak Club Guy (uncredited)

Adrienne Rusk as Kodiak Club Girl (uncredited)