Owen Wilson as Lightning McQueen (voice)

Cristela Alonzo as Cruz Ramirez (voice)

Chris Cooper as Smokey (voice)

Nathan Fillion as Sterling (voice)

Larry the Cable Guy as Mater (voice)

Armie Hammer as Jackson Storm (voice)

Ray Magliozzi as Dusty (voice)

Tony Shalhoub as Luigi (voice)

Bonnie Hunt as Sally Carrera (voice)

Lea DeLaria as Miss Fritter (voice)

Kerry Washington as Natalie Certain (voice)

Bob Costas as Bob Cutlass (voice)

Margo Martindale as Louise Nash (voice)

Darrell Waltrip as Darrell Cartrip (voice)

Isiah Whitlock, Jr. as River Scott (voice)

Bob Peterson as Chick Hicks (voice)

Guido Quaroni as Guido (voice)

Tom Magliozzi as Rusty (voice)

John Ratzenberger as Mack (voice)

Kyle Petty as Cal Weathers (voice)

Lewis Hamilton as Hamilton (voice)

Lloyd Sherr as Fillmore (voice)

Junior Johnson as Junior Moon (voice)

Ray Evernham as Ray Reverham (voice)

Paul Newman as Doc Hudson (voice) (archive sound)

Cheech Marin as Ramone (voice)

Humpy Wheeler as Tex (voice)

Katherine Helmond as Lizzie (voice)

Paul Dooley as Sarge (voice)

Jenifer Lewis as Flo (voice)

Shannon Spake as Shannon Spokes (voice)

Madeleine McGraw as Maddy McGear (voice)

Michael Wallis as Sheriff (voice)

Mike Joy as Mike Joyride (voice)

Jeff Gordon as Jeff Gorvette (voice)

Daniel Suárez as Danny Swervez (voice)

Ryan Blaney as Ryan 'Inside' Laney (voice)

Darrell Wallace, Jr. as Bubba Wheelhouse (voice)

Chase Elliott as Chase Racelott (voice)

Richard Petty as The King (voice)

Andra Day as Sweet Tea (voice)

Andrea Baker as Additional Voices (voice)

Doug Burch as Additional Voices (voice)

Cathy Cavadini as Additional Voices (voice)

Lanei Chapman as Additional Voices (voice)

Will Collyer as Additional Voices (voice)

Abby Craden as Additional Voices (voice)

Django Craig as Additional Voices (voice)

James G. Dashe as Additional Voices (voice)

Eduardo Ambriz DeColosio as Additional Voices (voice)

John DeMita as Additional Voices (voice)

Rod Gnapp as Additional Voices (voice)

Willow Geer as Additional Voices (voice)

Isa Hall as Additional Voices (voice)

Aaron Hendry as Additional Voices (voice)

John Hoffman as Additional Voices (voice)

Barney Jones as Additional Voices (voice)

Mikey Kelley as Additional Voices (voice)

Carlyle King as Additional Voices (voice)

Daamen J. Krall as Additional Voices (voice)

David H. Lawrence XVII as Additional Voices (voice)

Malana Lea as Additional Voices (voice)

Jeremy Maxwell as Additional Voices (voice)

Levi Nunez as Additional Voices (voice)

Angel Oquendo as Additional Voices (voice)

Jason Pace as Additional Voices (voice)

Bob Peterson as Additional Voices (voice)

James Ponce as Additional Voices (voice)

Alex Puccinelli as Additional Voices (voice)

David J. Randolph as Additional Voices (voice)

Jerome Ranft as Additional Voices (voice)

Noreen Reardon as Additional Voices (voice)

A.J. Riebli III as Additional Voices (voice)

Peter Sohn as Additional Voices (voice)

Galyn Susman as Additional Voices (voice)

Regina Taufen as Additional Voices (voice)

Nancy Truman as Additional Voices (voice)

Cheryl Tyre Smith as Additional Voices (voice)

Andrew Vernon as Additional Voices (voice)

Jay Ward as Additional Voices (voice)