Owen Wilson as Lightning McQueen (voice)

Paul Newman as Doc Hudson (voice)

Bonnie Hunt as Sally Carrera (voice)

Larry the Cable Guy as Mater (voice)

Cheech Marin as Ramone (voice)

Tony Shalhoub as Luigi (voice)

Guido Quaroni as Guido (voice)

Jenifer Lewis as Flo (voice)

Paul Dooley as Sarge (voice)

Michael Wallis as Sheriff (voice)

George Carlin as Fillmore (voice)

Katherine Helmond as Lizzie (voice)

John Ratzenberger as Mack / Hamm Truck / Abominable Snow Plow / P.T. Flea Car (voice)

Joe Ranft as Red / Peterbilt (voice)

Michael Keaton as Chick Hicks (voice)

Richard Petty as The King (voice)

Jeremy Piven as Harv (voice)

Bob Costas as Bob Cutlass (voice)

Darrell Waltrip as Darrell Cartrip (voice)

Richard Kind as Van (voice)

Edie McClurg as Minny (voice)

Humpy Wheeler as Tex (voice)

Tom Magliozzi as Rusty Rust-eze (voice)

Ray Magliozzi as Dusty Rust-eze (voice)

Lynda Petty as Mrs. The King (voice)

Andrew Stanton as Fred (voice)

Dale Earnhardt Jr. as Junior (voice)

Michael Schumacher as Michael Schumacher Ferrari (voice)

Jay Leno as Jay Limo (voice)

Mario Andretti as Mario Andretti (voice)

Sarah Clark as Kori Turbowitz (voice)

Mike Nelson as Not Chuck (voice)

Jonas Rivera as Boost (voice)

Lou Romano as Snotrod (voice)

Adrian Ochoa as Wingo (voice)

E.J. Holowicki as DJ (voice)

Elissa Knight as Tia (voice)

Lindsey Collins as Mia (voice)

Larry Benton as Motorhome Race Fan (voice)

Douglas Keever as Motorhome Race Fan (voice)

Tom Hanks as Woody Car (voice)

Tim Allen as Buzz Lightyear Car (voice)

Billy Crystal as Mike Car (voice)

John Goodman as Sullivan Truck (voice)

Dave Foley as Flik Car (voice)

Jack Angel as Additional Voices (voice)

Michael Bell as Additional Voices (voice)

Bob Bergen as Additional Voices (voice)

Susan Blu as Additional Voices (voice)

Andrea Boerries as Additional Voices (voice)

Marco Boerries as Additional Voices (voice)

Rodger Bumpass as Additional Voices (voice)

Torbin Xan Bullock as Additional Voices (voice)

Richard Cawood as Additional Voices (voice)

Scott Clark as Additional Voices (voice)

Kathy Coates as Additional Voices (voice)

John Cygan as Additional Voices (voice)

Jennifer Darling as Additional Voices (voice)

Paul Eiding as Additional Voices (voice)

Bill Farmer as Additional Voices (voice)

Brian Fee as Additional Voices (voice)

Teresa Ganzel as Additional Voices (voice)

Craig Good as Additional Voices (voice)

Jess Harnell as Additional Voices (voice)

Artie Kempner as Additional Voices (voice)

Hooman Khalili as Additional Voices (voice)

Sonoko Konishi as Additional Voices (voice)

Erik Langley as Additional Voices (voice)

Sherry Lynn as Additional Voices (voice)

Danny Mann as Additional Voices (voice)

Mickie McGowan as Additional Voices (voice)

Laraine Newman as Additional Voices (voice)

Teddy Newton as Additional Voices (voice)

Colleen O'Shaughnessey as Additional Voices (voice)

Bob Peterson as Additional Voices (voice)

Steve Purcell as Additional Voices (voice)

Jan Rabson as Additional Voices (voice)

A.J. Riebli III as Additional Voices (voice)

Dan Scanlon as Additional Voices (voice)

Stephen Schaffer as Additional Voices (voice)

Ken Schretzmann as Additional Voices (voice)

Bob Scott as Additional Voices (voice)

Matt Staudt as Additional Voices (voice)

Jay Ward as Additional Voices (voice)

Jim Ward as Additional Voices (voice)

Colette Whitaker as Additional Voices (voice)

Jeremy Clarkson as Harv (voice) (UK version)