Frank Welker as Freddie Jones / Scooby-Doo (voice)

Mindy Cohn as Velma Dinkley (voice)

Grey DeLisle as Daphne Blake (voice)

Matthew Lillard as Shaggy Rogers (voice)

Robin Atkin Downes as Fortius / Announcer (voice)

Troy Baker as Sergey Plotnikov (voice)

Josh Keaton as Steve Looker (voice)

Janet Montgomery as Diane (voice)

James Patrick Stuart as Jack Riggins / Igor (voice)

Domitilla D'Amico as Daphne Blake (uncredited)