Gillian Anderson as Jean Maclestone

Alan Cumming as Dewey Dalamanatousis

Heather Graham as Beth Freemantle

Danny Huston as Art Spindle

Jack Huston as Jo Richards

Christopher Lee as Mr. Alfred Rhinegold

Joanna Lumley as Mrs. Alfreda Rhinegold

Simon McBurney as Robert Freign

Meredith Ostrom as Joany

Charlotte Rampling as Emille

Amanda Seyfried as Paige Prideaux

Stellan Skarsgård as Bob Maclestone

Jaime Winstone as Elaine

Alfie Allen as Photographer

Gemma Atkinson as Charlotte Bailey

Silas Carson as Surgeon

Sidney Cole as Taxi Driver

Sergio James as Alphonse (Maitre D')

Michael Culkin as Beth's Father

Joséphine de la Baume as Frenchie

Alma Eno as Elaine's Friend

Michael Estorick as Rabbi

Rosie Fellner as Rachel Leighton

Stephen Greif as Bob's Lawyer

Maria Papas as Waitress

Jenny Runacre as Mrs. Havermeyer

Ebe Sievwright as Assistant Surgeon

Jan Uddin as Art's Partner