T.J. Miller as Gene (voice)

James Corden as Hi-5 (voice)

Anna Faris as Jailbreak (voice)

Maya Rudolph as Smiler (voice)

Steven Wright as Mel Meh (voice)

Jennifer Coolidge as Mary Meh (voice)

Jake T. Austin as Alex (voice)

Christina Aguilera as Akiko Glitter (voice)

Sofía Vergara as Flamenco Dancer (voice)

Patrick Stewart as Poop (voice)

Rob Riggle as Ice Cream (voice)

Sean Hayes as Steven (voice)

Tati Gabrielle as Addie (voice)

Jude Koyaute as Poop Jr. (voice)

Rachael Ray as Spam (voice)

Jeff Ross as Internet Troll (voice)

Melissa Sturm as Angel / Phone Store Employee (voice)

Tony Leondis as Laughter / Broom / Pizza (voice)

Sean Giambrone as Travis (voice)

Timothy Durkin as Mr. Schnoebelen (voice)

Liam Aiken as Ronnie Ram Tech (voice)

Wendell Brooks as Ram Tech Bouncer (voice)

Tarek Bishara as Fist Bump (voice)

Kevin Chamberlin as Gavel (voice)

William Townsend as Rocket (voice)

Adam Brown as Flashlight / Trojan Horse (voice)

William J. Caparella as Alien (voice)

Joe Whyte as Red Wagon (voice)

Conrad Vernon as Trojan Horse (voice)

Kate Gorney as Heart Eyes (voice)

Rich Dietl as Nerd Emoji (voice)

Derek Mio as Elephant (voice)

Paige Eileen Caparella as Cat Heart Eyes (voice)

Bob Bergen as Additional Voices (voice)

Debi Derryberry as Additional Voices (voice)

Jess Harnell as Additional Voices (voice)

Phil LaMarr as Additional Voices (voice)

Laraine Newman as Additional Voices (voice)

Tara Strong as Additional Voices (voice)

Fred Tatasciore as Additional Voices (voice)

E. G. Daily as Additional Voices (voice)

Carlos Alazraqui as Additional Voices (voice)

Keith Anthony as Additional Voices (voice)

Eric Bauza as Additional Voices (voice)

David Boat as Additional Voices (voice)

Terri Douglas as Additional Voices (voice)

Keith Ferguson as Additional Voices (voice)

Amy Hill as Additional Voices (voice)

John Kassir as Additional Voices (voice)

Josh Keaton as Additional Voices (voice)

Mona Marshall as Additional Voices (voice)

Scott Menville as Additional Voices (voice)

Max Mittelman as Additional Voices (voice)

Alicyn Packard as Additional Voices (voice)

Paul Pape as Additional Voices (voice)

Debra Wilson as Additional Voices (voice)

Matthew Wood as Additional Voices (voice)

John Cramer as Additional Voices (voice)