Kevin James as Griffin Keyes

Rosario Dawson as Kate

Leslie Bibb as Stephanie

Joe Rogan as Gale

Nat Faxon as Dave

Ken Jeong as Venom

Steffiana De La Cruz as Robin

Thomas Gottschalk as Jurgen

Donnie Wahlberg as Shane

Brandon Keener as Nimer

Tom Woodruff Jr. as Bernie the Gorilla

Nick Bakay as Franky

Jackie Sandler as TGIF Waitress

Nicholas Turturro as Manny

Nick Nolte as Bernie the Gorilla (voice)

Adam Sandler as Donald the Monkey (voice)

Sylvester Stallone as Joe the Lion (voice)

Cher as Janet the Lioness (voice)

Judd Apatow as Barry the Elephant (voice)

Faizon Love as Bruce the Bear (voice)

Jon Favreau as Jerome the Bear (voice)

Maya Rudolph as Mollie the Giraffe (voice)

Bas Rutten as Sebastian the Wolf (voice)

Don Rickles as Frog (voice)

Jim Breuer as Crow (voice)

Richie Minervini as Ostrich (voice)

Katrina Begin as TGIF Secretary

Matthew R. Staley as Glenn

Gary Valentine as Pizza Guy

Tanner Blaze as Little Boy at Zoo

Tim Gage as Bike Guy

Gino Falsetto as Valet

Etienne Deneault as Acrobat

Robin Bakay as Rebecca

Michael Burton as Car Customer

Todd Zeile as High Roller

Mookie Barker as Grandfather

Tara Giordano-Dean as Shana

Daniel Guire as Salesman

Mark DellaGrotte as Salesman

Ellen Colton as Shane's Mother

Barry Bernardi as Cab Driver

Juston McKinney as Upscale Restaurant Manager

Garon Michael as Bernie the Gorilla

Dan Marshall as Zoo Visitor (uncredited)

Crystal the Monkey as Donald the Monkey (uncredited)

Bart the Bear II as Jerome the Bear