Adam Sandler as Danny Maccabee

Jennifer Aniston as Katherine Murphy

Brooklyn Decker as Palmer Dodge

Nicole Kidman as Devlin Adams

Nick Swardson as Eddie Simms

Bailee Madison as Maggie Murphy

Griffin Gluck as Michael Murphy

Dave Matthews as Ian Maxtone Jones

Kevin Nealon as Adon

Rachel Dratch as Kirsten Brant

Allen Covert as Soul Patch

Dan Patrick as Tanner Patrick

Minka Kelly as Joanna Damon

Jackie Sandler as Veruca

Rakefet Abergel as Patricia

Dana Goodman as Bridesmaid

Julia Lea Wolov as Bridesmaid

Colby Kline as Bridesmaid

Jana Sandler as Bridesmaid

Jonathan Loughran as Pick Up Guy #1

Peter Dante as Pick-Up Guy #2

Michael Laskin as Mr. Maccabee

Carol Ann Susi as Mrs. Maccabee

Gene Pompa as Delivery Guy

Mario Joyner as Henderson

Keegan-Michael Key as Ernesto

Heidi Montag as Adon's Wife

Andy Roddick as Good Looking Guy on Plane

Jillian Nelson as Young College Girl

Lilian Tapia as Rosa

Azer Greco as Silas

Lori Heuring as Salesgirl

Darrin Lackey as Waiter

Julie Dixon Jackson as Mrs. Harrington

Branscombe Richmond as Bartender

Aaron Zachary Philips as Fat Kid

Jessica Jade Andres as Teenage Girl at Dive Restaurant

Kent Avenido as Guy at Dive Restaurant

Rachel Specter as Lisa Hammond

Tia Van Berg as Scary Woman

Todd Sherry as Check-In Clerk

Brendon Eggertsen as Ariel

Andrew Tomoso as Rope Bridge Guy

Alexandra Titone as Hawaiian Family at Rope Bridge

Sadie Sandler as Hawaiian Family at Rope Bridge

Sunny Sandler as Hawaiian Family at Rope Bridge

Lorna Scott as Big Country

Newton DeLeon as Diner at Dive Restaurant

Teresa Zantua as Hawaiian Rosa

Roger Parham-Brown as Pizza Hut Janitor

Tom Dill as Coach Dill

Vanessa Villalovos as Saleswoman

Cort Rogers as Tripping Kid

Sharon Ferguson as Pregnant Woman at McFunnigans

Sheroum Kim as Waitress

Jevon Scott as Sailor

Brandon Force as Sailor

Samuel Nims as Sailor

Elijah Scholer as Sailor

Arlene Newman as Hotel Guest (uncredited)