Adam Sandler as Jack / Jill

Al Pacino as Al Pacino

Katie Holmes as Erin

Elodie Tougne as Sofia Sadelstein

Rohan Chand as Gary Sadelstein

Eugenio Derbez as Felipe / Felipe's Grandma

David Spade as Monica

Nick Swardson as Todd

Tim Meadows as Ted

Allen Covert as Otto

Norm Macdonald as Funbucket

Geoff Pierson as Carter Simmons

Valerie Mahaffey as Bitsy Simmons

Gary Valentine as Dallas

Dana Carvey as Scraggly Puppeteer

Regis Philbin as Regis Philbin

Gad Elmaleh as Xavier

Dan Patrick as Dan Patrick

Shaquille O'Neal as Shaquille O'Neal

Drew Carey as Drew Carey

John McEnroe as John McEnroe

Christie Brinkley as Christie Brinkley

Michael Irvin as Michael Irvin

Bill Romanowski as Bill Romanowski

Jared Fogle as Jared Fogle

Billy Blanks as Billy Blanks

Vince Offer as Sham-Wow Guy

Caitlyn Jenner as Bruce Jenner

Jackie Seiden as Tracy

Sadie Sandler as Little Girl on Ship

Sunny Sandler as Little Girl on Ship

Georgia Hatzis as Carol

Jonathan Loughran as Monica's Boyfriend

Peter Dante as Carol's Boyfriend

J.D. Donaruma as Tracy's Boyfriend

Tyler Spindel as Coco's Waiter

Owen Benjamin as Angry Moviegoer #1

Chris Titone as Angry Moviegoer #2

John Farley as Mort the Hot Dog Vendor

Dennis Dugan as Al Pacino's Standby

Robert C. Lopez as Jose

Jalen Testerman as Jose Jr.

Simrin C. Player as Josephina

Gerardo Hernandez Beltran as Felipe's Brother

Kadyr Gutierrez as Soccer Player

Virginia Louise Smith as Actress / Queen Elizabeth

Daniel Silverberg as Stage Manager

Richard Kline as Theatergoer #1

Donald Agnelli as Theatergoer #2

Joseph Balderrama as Spanish Valet

Luis Fernandez-Gil as Cruise Ship Director

Ruben Rabasa as Bathroom Attendant

Nick Gillie as Dunkin' Donuts Customer

Andy Goldenberg as Dunkin' Donuts Employee #1

Marisa Field as Dunkin' Donuts Employee #2

George Gray as The Price Is Right Announcer

Manuela Arbeláez as The Price is Right Showcase Girl

Gwendolyn Osborne-Smith as The Price is Right Showcase Girl

Rachel Reynolds as The Price Is Right Showcase Girl

Anna Mathias as The Price is Right Contestant

Robert Harvey as Fan

Lawrence Tanter as Lakers PA Announcer

Eric Lamonsoff as Documentary Twin

Schmeric Lamonsoff as Documentary Twin

Kara Pacitto as Documentary Twin

Rafael Feldman as Documentary Twin

Yan Feldman as Documentary Twin

David Sontag as Documentary Twin

Larry Sontag as Documentary Twin

Logan Raskin as Documentary Twin

Roger Raskin as Documentary Twin

Erica Jaye Green as Documentary Twin

Lina Green as Documentary Twin

Tiana Madry as Documentary Twin

Tiara Madry as Documentary Twin

January Welsh as Documentary Twin

Marissa Welsh as Documentary Twin

Gary Lane as Documentary Twin

Larry Lane as Documentary Twin

Dingani Beza as Documentary Twin

Zondwayo Beza as Documentary Twin

Jammer as Documentary Twin

Slammer as Documentary Twin

Patty Palmer as Documentary Twin

Diane Palmer as Documentary Twin

Alex Burkart as Documentary Twin

Nathan Burkart as Documentary Twin

Richard Harris as Documentary Twin

Ron Harris as Documentary Twin

Rachel Rife as Documentary Twin

Rebekah Rife as Documentary Twin

Elijah Gipson as Documentary Twin

Elleah Gipson as Documentary Twin

Katie Cockrell as Documentary Twin

Kellie Cockrell as Documentary Twin

Joel Harold as Documentary Twin

Joseph Harold as Documentary Twin

Alexis Stier as Documentary Twin

Megan Stier as Documentary Twin

Albert Pugliese as Documentary Twin

Gregory Pugliese as Documentary Twin

Jordan Tindall as Documentary Twin

Lance Tindall as Documentary Twin

Miles Tindall as Documentary Twin

Johnny Depp as Johnny Depp (uncredited)

Erica Abke as Teen Jack's Love Interest (uncredited)

Claudia Adams as Angry Theatre Patron #1 (uncredited)

Nick Baga as Dunkin' Donuts' Dunkaccino Guy (uncredited)

Derek Baker as Fan (uncredited)

Luke Broadlick as Dunkin' Donuts Employee (uncredited)

Erin Shae Bryan as Sister Watching Double Dutch (uncredited)

Kobe Bryant as Kobe Bryant (archive footage) (uncredited)

Peter Chudyba as Cruise Waiter (uncredited)

Billy Concha as Commercial Crew Member (uncredited)

Sarah Davidson as Sexy Donut Girl (uncredited)

Louis Fasanaro as Theatergoer (uncredited)

Patrick H. Fox as Cruise Passenger (uncredited)

Lacey Marisa Friedman as Dancing Girl (uncredited)

Gianna Gomez as Felipe's Niece (uncredited)

Fouad Hajji as Bar Patron (uncredited)

Betsy Hammer as Bar Patron (uncredited)

Matthew P. Hanson as Dunkin Donuts Announcer (uncredited)

Fatimah Hassan as Nurse (uncredited)

Vahid Jafroodi as Party Guest (uncredited)

Jaelyn Jones as Party Guest (uncredited)

Amina Julianna as Juanita (uncredited)

Kristin Michelle Keating as Advertising Office Worker (uncredited)

Carmen Kirby as Movie Goer (uncredited)

Diamond Nicole Landeen as Balloon Girl (uncredited)

Glen Mauro as Twin #1 (uncredited)

Gary Mauro as Twin #2 (uncredited)

Brett Nichols as Male Nurse (uncredited)

David Osmond as Price Is Right Contestant (uncredited)

Julian Perrin as Cashier (uncredited)

Yvette Rachelle as Yvette (uncredited)

Jazmine Ramay as Murmerer (uncredited)

Tia Robinson as Theatregoer (uncredited)

Santiago Segura as Eduardo (uncredited)

Patrice Sepulveda as Cruiseship Passenger (uncredited)

Zach Siegwarth as Movie Theater Customer #4 (uncredited)

Ashley Speegle as Jared Fogle's Date (uncredited)

Ivan Velez as Dunkin Donuts Employee (uncredited)

Lloyd G. Vincent as Soccer Player (uncredited)

Alexis Wilkins as Sistine Chapel Girl (uncredited)

Laramie Williams as The Price is Right Contestant (uncredited)