Anna Chlumsky as Vada Sultenfuss

Macaulay Culkin as Thomas J. Sennett

Dan Aykroyd as Harry Sultenfuss

Jamie Lee Curtis as Shelly DeVoto

Richard Masur as Phil Sultenfuss

Griffin Dunne as Mr. Jake Bixler

Ann Nelson as Gramoo Sultenfuss

Peter Michael Goetz as Dr. Welty

Jane Hallaren as Nurse Randall

Anthony R. Jones as Arthur

Tom Villard as Justin

Lara Steinick as Ronda

Kristian Truelsen as Charles

David Caprita as Ray

Jody Wilson as Mrs. Hunsaker

Linda Perri as Betty

Nancy L. Chlumsky as Jackie

Glenda Chism as Thomas J.'s Mother

Bill Cordell as Thomas J.'s Father

Ray Buktenica as Danny

Shane Obedzinski as Billy

Edgar Allan Poe IV as Carnival Barker

Anthony Giaimo as Carnival Barker