Seth MacFarlane as Stewie Griffin / Various Characters (voice)

Alex Borstein as Lois Griffin / Various Characters (voice)

Seth Green as Chris Griffin / Various Characters (voice)

Mila Kunis as Meg Griffin / Various Characters (voice)

Patrick Warburton as Joe Swanson (voice)

Lori Alan as Diane Simmons (voice)

Drew Barrymore as Drew Barrymore (voice)

Mike Henry as Cleveland Brown / John Herbert (voice)

Rachael MacFarlane as Katie Couric / Baby-Expecting Woman / Britney Spears (voice)

Noel Blanc as Elmer Fudd (voice)

Phil LaMarr as Ollie Williams /Various Characters (voice)

John G. Brennan as Horace / Additional Voices (voice)

Gary Janetti as Various Characters (voice)

Don LaFontaine as Promo Announcer (voice)

Ron Livingston as Clerk (voice)

Kevin Michael Richardson as Ray Charles / Various Characters (voice)

Kate Rigg as Various Characters (voice)

Will Sasso as Randy Newman / James Lipton (voice)

André Sogliuzzo as Various Characters (voice)

Rory Thost as Casper (voice)

John Viener as Meg 'Ron' Griffin (voice)

Adam West as Mayor Adam West (voice)

Wally Wingert as Various Characters (voice)

René Auberjonois as Odo (voice)

Ali Hillis as Meg Griffin (singing voice) / Various Characters (voice)

Ralph Garman as Various Characters (voice)

Jennie Garth as Kelly Taylor (voice)

Larry Kenney as Lion-O (voice)

Lynne Lipton as Cheetara (voice)

Jason Priestley as Brandon Walsh (voice)

Michael Clarke Duncan as The Stork (voice)

Chris Sheridan as Various Characters (voice)

Danny Smith as Al Harrington (voice)

Tori Spelling as Donna Martin (voice)

Joy Behar as Joy Behar (voice)

Fred Tatasciore as Various Characters (voice)

Adam Borstein as Various Characters (voice)

Bill Fagerbakke as Indian (voice)

David A. Goodman as Jesus Christ (voice)

Busy Philipps as Various Characters (voice)

Audrey Wasilewski as Various Characters (voice)