Dian Sastrowardoyo as RA. Kartini

Ayushita Nugraha as RA. Kardinah

Acha Septriasa as RA. Roekmini

Deddy Sutomo as RM. Sosroningrat (RM. Adipati Ario Sosroningrat)

Christine Hakim as Yu Ngasirah (Kartini's Mother)

Djenar Maesa Ayu as RA. Moeryam

Denny Sumargo as RM. Slamet

Adinia Wirasti as RA. Soelastri

Reza Rahadian as RM. Kartono

Dwi Sasono as RM. Joyoadiningrat

Nova Eliza as Young Ngasirah

Giras Basuwondo as Busono

Bintang Timur Widodo as Moeljono

Rudy Wowor as Sitjhoft

Hans de Kraker as Tn. Ovink Soer

Barbara van Kooten as Ny. Ovink Soer

Rukman Rosadi as Sosroningrat Muda

Whinda Oktaviana as Moeryam Muda

Rebecca Reijman as Stella Zehandelaar

Carmen van Rijnbach as Cecile de Jong

Alinda Wit as Hilda von Suylenberg

Leroy Osmani as Bupati Lebak

Dian Sidik as Haryono

Jeroen Lezer as Roseboom

Katinka van Heeren as Nellie van Zuylenberg

Neysa Chandria as Kartini (6 Th)

Elang El Gibran as Slamet (14 Th)

Badra Andhipani Jagat as Busono (11 Th)

Akinza Chevalier as Kartono (8 Th)

A. Wangi Asriningati as Soelastri (8 Th)

Andre as Roekmini (5 Th)

Yola Quinza Assyifa as Kardinah (4 Th)

Azkano K. T. as Moeljono (4 Th)

Ayodyaningrum S. W. B. as Bayi Moeljono

Bunga Adelheid as Kartini (14 Th)

Rayhan Efendi as Kartono (16 Th)

Reyda Aqila as Kardinah (13 Th)

Laurensia Aninditha as Roekmini (12 Th)

Hazulay Shava Jacinda Archano as Sulastri (8 Th)

Bondan Nusantara as Pak Atmo

Yu Beruk as Mbok Lawiyah

Lona Vega as Rosa Abendanon

Pieter van Luijk as J. H. Abendanon

Novi Budianto as Hadiningrat

Hasmi as Purboningrat

Suharyoso as Condronegoro

Wim van Leusden as Baron van Dietmar

Rudi Corens as Henry van Koll

Joan Linhorst as Nelly van Koll

Carina Ellemes as Ter Horst

Arjan Onderdenwijngaard as Dokter Belanda

Noel Kefas as Priyayi 1

Pulung Handiyawan as Priyayi 2

Tri Sudarsono as Bupati Blora

Liek Suyanto as Singowiryo

Bambang Darto as Kyai Soleh Darat

Gabor Varga as Suami Hilda Von Suylenberg

Gabriella Quinlyn as Anak Hilda 1

Saira as Putri Yasmin

Agus Kencrot as Ario Reksonegoro / Bupati Tegal

Ernanta Kusuma as Utusan Rembang

Landung Simatupang as Condronegoro IV

Haru Sandra as RM. Cokrohadisosro

Watie Wibowo as Istri Hadiningrat

Tarina Titiliani as Istri Busono

Dilla Fadiela as Istri Slamet

Wiwid Setya as Istri Haryono

Yuliah Sumarah as Istri Reksonegoro

Ucik Kaneman as Istri Condronegoro

Mariah Merry as Istri Purboningrat

Jess V.D. as Jean Damini

Tanaya Aly Amara Ghazhy as Gadis Kecil Desa Wukirsari

Jamaluddin Latif as Patihnya Sosroningrat

Pak Joko as Abdi Dalem Laki - 1

Sujarwo as Abdi Dalem Laki - 2

Jeblay as Abdi Dalem Laki - 3