Queen Latifah as Iza Banks

Betsy Brandt as LeeAnne Walters

Rob Morrow as Professor Edwards

Marin Ireland as Melissa Mays

Lyndie Greenwood as Adina Banks

Jill Scott as Nayyirah Shariff

Sonia Dhillon Tully as Dr. Mona Hanna-Attisha

Harry Judge as Curt Guyette

Lynne Griffin as

Emma Campbell as Radio Interviewer

Janet Porter as Mayor's Receptionist

Dylan Taylor as Adam Mays

Anthony Christian Potenza as Dennis Walters

Anwen O'Driscoll as Kaylie Walters

Mathew Edmondson as Caleb Mays

Brian Hamman as Mike Glascow

Steve Arbuckle as

Juan Carlos Velis as Miguel Del Toral

Kaelen Ohm as Colleage

Cassius Crieghtney as Jake

Arlene Duncan as Claire McClinton

Neil Whitely as Security Guard

Christina Dixon as Nurse #2

Daniel Coz as Colin

Alex Hatz as Pediatrician

Lucas Misaljevic as Garrett Walters

Isaak Bailey as Gavin Walters

Celine Tsai as Min Tang

Lisa Michelle Cornelius as Nurse #1

Keethan Krish as Sid

Diane Higgins as Background Performer

James Madge as Resident

Dave Alaimo as Father of sick child

Kiran Patel as Reporter #1

Connor Donnell as Cole Mays

Stefen Rollpiller as Records Employee

Jessica Crowley as City Hall Attendee

Carrie Beale as Pedestrian / City Hall Attendee (uncredited)