John Cusack as Craig Schwartz

John Malkovich as John Horatio Malkovich

Cameron Diaz as Lotte Schwartz

Catherine Keener as Maxine Lund

Orson Bean as Dr. Lester

Mary Kay Place as Floris

W. Earl Brown as First J.M. Inc. Customer

Carlos Jacott as Larry the Agent

Willie Garson as Guy in Restaurant

Byrne Piven as Captain Mertin

Gregory Sporleder as Drunk at Bar

Charlie Sheen as Charlie

Reggie Hayes as Don

K.K. Dodds as Wendy

Judith Wetzell as Tiny Woman

Octavia Spencer as Woman in Elevator

Ned Bellamy as Derek Mantini

Eric Weinstein as Father at Puppet Show

Madison Lanc as Daughter at Puppet Show

Kevin Carroll as Cab Driver

Gerald Emerick as Sad Man in Line

Richard Fancy as Johnson Heyward

Patti Tippo as Malkovich's Mother

Daniel Hansen as Boy Malkovich

Mariah O'Brien as Girl Creeped Out by Malkovich

Kelly Teacher as Emily

Bill M. Ryusaki as Mr. Hiroshi

Jacqueline Benoît as Lester's Friend

William Buck as Lester's Friend

Christine D. Coleman as Lester's Friend

Jeanne Diehl as Lester's Friend

Audrey Gelfund as Lester's Friend

Yetta Ginsburg as Lester's Friend

Sylvester Jenkins as Lester's Friend

Roy C. Johnson as Lester's Friend

Eddie J. Low as Lester's Friend

Ralph W. Spaulding as Lester's Friend

David Wyler as Lester's Friend

Flori Wyler as Lester's Friend

Kevin Lee as Ballet Dancer

Marlowe Bassett as Ballet Dancer

Jennifer Canzoneri as Ballet Dancer

Kristie Cordle as Ballet Dancer

Denise Dabrowski as Ballet Dancer

Kristin Condon as Ballet Dancer

Charlene Grimsley as Ballet Dancer

Christine Krejer as Ballet Dancer

Erica Long as Ballet Dancer

Yvonne Montelius as Ballet Dancer

Jessica Neuberger as Ballet Dancer

Sara Rifkin as Ballet Dancer

Elizabeth Rivera as Ballet Dancer

Chelsa Sjostrom as Ballet Dancer

Pamela Hayden as Featured Character Voice (voice)

Jayne Hess as Featured Character Voice (voice)

Michelle Madden as Featured Character Voice (voice)

Greg O'Neill as Featured Character Voice (voice)

Neil Ross as Featured Character Voice (voice)

Bill Wittman as Featured Character Voice (voice)

David Fincher as Christopher Bing (uncredited)

Sean Penn as Sean Penn (uncredited)

Brad Pitt as Brad Pitt (uncredited)

James Murray as Student Puppeteer (uncredited)