Keanu Reeves as Neo / Thomas Anderson

Carrie-Anne Moss as Trinity / Tiffany

Yahya Abdul-Mateen II as Morpheus / Agent Smith

Jonathan Groff as Smith

Jessica Henwick as Bugs

Neil Patrick Harris as The Analyst

Jada Pinkett Smith as Niobe

Priyanka Chopra Jonas as Sati

Christina Ricci as Gwyn de Vere

Lambert Wilson as The Merovingian

Andrew Lewis Caldwell as Jude

Toby Onwumere as Sequoia

Max Riemelt as Sheperd

Joshua Grothe as FunktIøn

Brian J. Smith as Berg

Eréndira Ibarra as Lexy

Michael X. Sommers as Skroce

L. Trey Wilson as Hanno

Mumbi Maina as Ellster

Max Mauff as Quillion

Purab Kohli as Zen

Freema Agyeman as Astra

Sabrina Strehl as Fiona

Andrew Rothney as Scott

Cooper Rivers as GJ

Esther Silex as Brainstormer #1

Frank Isom as Brainstormer #2

Leo Sheng as Bobbi

Telma Hopkins as Freya

John Gaeta as Deus Machina Employee #1

Donald Mustard as Deus Machina Employee #2

Kim Libreri as Deux Machina Employee #3

Joe Mazza as Cop

Chad Stahelski as Chad

Julian Grey as Brandon

Gaige Chaturantabut as Donnie

Tiger Chen Hu as M.O.T.C.

Volkhart Buff as Kush

Amadei Weiland as Agent White

Stephen Dunlevy as Agent Jones

Ellen Hollman as Echo

Ian Pirie as Lieutenant

Nicolas de Pruyssenaere as Lead SWAT

Felix Quinton as SWAT

Aaron Pina as FBI

Dani Swan as Woman in Red

London Breed as Calliope

Steven Roy as Thomas's Reflection

Mercy Malick as Wife

Juval Dieziger as Utrix Driver

James McTeigue as Innocuous Man

Sarah McTeigue as Tiffany's Reflection

William W. Barbour as Businessman (uncredited)

Kenny Beers as SWAT Team Member / Runner (uncredited)

Thomas Dalby as SWAT Officer (uncredited)

James D. Weston II as Military / SWAT (uncredited)

Michael J. Gwynn as Business Runner (uncredited)