Whoopi Goldberg as Deloris Van Cartier

Kathy Najimy as Sister Mary Patrick

Lauryn Hill as Rita Louise Watson

Sheryl Lee Ralph as Florence Watson

Maggie Smith as Mother Superior

Barnard Hughes as Father Maurice

Mary Wickes as Sister Mary Lazarus

James Coburn as Mr. Crisp

Michael Jeter as Father Ignatius

Wendy Makkena as Sister Mary Robert

Robert Pastorelli as Joey Bustamente

Thomas Gottschalk as Father Wolfgang

Brad Sullivan as Father Thomas

Alanna Ubach as Maria

Ryan Toby as Wesley Glen 'Ahmal' James

Ron Johnson as Richard 'Sketch' Pinshum

Jennifer Love Hewitt as Margaret

Devin Kamin as Frankie

Tanya Blount as Tanya

Pat Crawford Brown as Choir Nun

Susan Browning as Choir Nun

Edith Diaz as Choir Nun

Ellen Albertini Dow as Choir Nun

Beth Fowler as Choir Nun

Prudence Wright Holmes as Choir Nun

Ruth Kobart as Choir Nun

Carmen Zapata as Choir Nun

Gabriel Trupin as Dancer

Sebastian La Cause as Dancer

Frank Williams as Dancer

Lacy Darryl Phillips as Dancer

Sydney Lassick as Competition Announcer

Michael Taliferro as Security Guard

Kai Bowe as Stage Manager

John Fontana as Flying Tech #1

Michael A. Tice as Flying Tech #2

Iris Graves as Iris Choir

Pamela Taylor as Iris Choir

Robert J. Benson as Iris Choir

Bill Irwin as Unnamed Brother #1

Tanya Newbould as Stage Manager

David Ulmer as Reporter

Terri J. Vaughn as Student

Kevin Stea as Dancer

Bill Duke as Mr. Johnson

Yolanda Whitaker as Sondra

Paul Michael Thorpe as Dancer 'Postman'

Christian Fitzharris as Tyler

Jenifer Lewis as Vegas Backup Singer #1

Deedee Magno as Classroom Kid

Sacha Thomas as Classroom Kid

Susan Johnson as Choir Nun