Gina Rodriguez as Carmen Sandiego (voice)

Finn Wolfhard as Player (voice)

Abby Trott as Ivy (voice)

Micheal Hawley as Zack / Guard 1 (voice)

Liam O'Brien as Professor Maelstrom / Diplomat / Guard 2 (voice)

Mary Elizabeth McGlynn as Coach Brunt (voice)

Toks Olagundoye as Countess Cleo (voice)

Sharon Muthu as Doctor Bellum / Agent Zari (voice)

Kari Wahlgren as Sheena (Tigress) / Caterer (voice)

Andrew Pifko as Antonio (El Topo) (voice)

Bernardo de Paula as Jean Paul (Le Chevre) (voice)

Kimiko Glenn as Paperstar (voice)

Charlet Chung as Julia Argent (voice)

Dawnn Lewis as Chief (voice)