Robert De Niro as Jonathan Flynn

Paul Dano as Nick Flynn

Julianne Moore as Jody Flynn

Olivia Thirlby as Denise

Eddie Rouse as Carlos

Steve Cirbus as Jeff

Lili Taylor as Joy

Victor Rasuk as Gabriel

Liam Broggy as Young Nick

Chris Chalk as Ivan

Wes Studi as Captain

Thomas Middleditch as Richard

Sarah Quinn as Religious Girl

Benjamin Foronda as Punky Guy

Dale Dickey as Marie

Josh Alscher as Crack Smoker

Dawn McGee as Waitress

Billy Wirth as Travis

Michael Gibson as Sergeant Bob

Kelly McCreary as Inez

Deirdre O'Connell as Frowzy Woman

Katherine Waterston as Sarah

Robert Andrews as Homeless Man 1

Michael Genadry as Young Counselor

Kelli Crump as Desk Clerk

Dara Tomanovich as Beautiful Woman

Jane Lee as Laura

Evan Wadle as Young Guy

Victor Pagan as Beady-Eyed Bill

Rony Clanton as Skid

Michael Buscemi as Dennis

Lorenzo Murphy as Morphine Addict

William Sadler as Ray

Joseph Prioleau as George

Lee Stringer as Homeless Man in Line

John O'Brien as Airline Pilot

Joey Boots as NA Guy

Luis Moco as Punk Rocker

Marilyn Torres as Little Girl's Mother

Stephen Williams as Counselor

Roy Milton Davis as Homeless Man 2

Rufino Colon as Shelter Guest 1

Jeffrey Ware as Jerry

Samira Wiley as Asha

Stuart Rudin as Moses

Gabriel Millman as Housing Counselor

Thomas Hoffman as Barlow

Joyce Myricks as Nurse / Counselor

Dwight Folsom as Isaac Clegg

Carlton Benbry as Counselor 2

George Asatrian as Beating Teen 1

Anthony Piccolo as Beating Teen 2

Kevin Keels as Banker at Party

Paul Senza as Shelter Counselor

Ian Bonner as 12-Step Member (uncredited)

Kevin Cannon as Crackhead Mugger (uncredited)

Louise Devery as Buttercup Bartender (uncredited)

Elli as Homeless Guy (uncredited)

Nick Flynn as Man Interviewing for Placement (uncredited)

Marty Krzywonos as Shelter Guest (uncredited)

John Mitchell as Shelter Guest 104 (uncredited)

Jeffrey Mowery as Homeless Man (uncredited)

Martin Pfefferkorn as Wounded Shuffler (uncredited)

Bill Walters as Homeless Man in Shelter (uncredited)