Mike Judge as Beavis / Butt-Head / Van Driessen (voice)

Andrea Savage as Serena Ryan (voice)

Gary Cole as Mattison (voice)

Nat Faxon as Jim Hartson (voice)

Chi McBride as Metcalf / Judge (voice)

Chris Diamantopoulos as Police Officer / Prisoners / Corrections Officers (voice)

Brian Huskey as Richard Wack (voice)

Tig Notaro as Professor (voice)

Stephen Root as Jail Tattoo Artist (voice)

Martin Starr as Corrections Officer / Ball-kicking Biker (voice)

Jimmy O. Yang as Flight Specialist Jung / Jeff (voice)

Mary Birdsong as Reporter (voice)

Zehra Fazal as Butt-Head Fantasy Woman #1 (voice)

Ashley Gardner as Anita Ross (voice)

David Herman as German Tourist / Gage / Jail Warden (voice)

Toby Huss as Todd Ianuzzi (voice)

Phil LaMarr as Flight Specialist Jackson / NSA Agents / Police Officer (voice)

Toks Olagundoye as Campaign Aide / Butt-Head Fantasy Woman #2 & #3 (voice)

Tru Valentino as McCabe / Head Corrections Officer (voice)

Carlos Alazraqui as Flight Specalist Valdivia (voice)

Susan Bennett as Siri (voice)

Greg Chun as Bus Driver (voice)