Leslie Nielsen as Mr. Quincy Magoo

Kelly Lynch as Luanne LeSeur / Prunella Pegula

Matt Keeslar as Waldo Magoo

Nick Chinlund as Bob Morgan

Stephen Tobolowsky as Agent FBI Chuck Stupak

Ernie Hudson as Agent CIA Gus Anders

Jennifer Garner as Stacey Sampanahoditra

Malcolm McDowell as Austin Cloquet

Miguel Ferrer as Ortega Peru

L. Harvey Gold as Schmitt

Art Irizawa as Gosha

John Tierney as Hebzinski

Terence Kelly as McManus

Rick Burgess as Molinaro

Jerry Wasserman as Javier

Bill Dow as Museum Curator

Frank C. Turner as Ralston - Stage Manager

Monique Rusu as Rosita

Robert Metcalfe as Desk Clerk

Danny Steele as Tenor

Dolores Drake as Female Tourist

Claire Riley as Newswoman

Pat Waldron as Soprano

Michael Puttonen as Security Guard

Pamela Diaz as Tour Guide

Chancz Perry as Train Station Porter

Marke Driesschen as Radio Announcer

Brenda McDonald as Opera Patron

Joseph Davies as TV Trainer

Shawn Macdonald as Cook Show Host

David Neale as Fix It Guy

Carrie Cain-Sparks as Rosita's Dresser

Kristie Yzerman as Snowboarder

David Mylrea as Baboon Performer

Greg Burson as Animated Magoo (voice)