Eddie Murphy as Prince Akeem / Clarence / Randy Watson / Saul

Arsenio Hall as Semmi / Extremely Ugly Girl / Morris / Reverend Brown

Shari Headley as Lisa McDowell

John Amos as Cleo McDowell

James Earl Jones as King Jaffe Joffer

Madge Sinclair as Queen Aoleon

Eriq La Salle as Darryl Jenks

Allison Dean as Patrice McDowell

Frankie Faison as Landlord

Louie Anderson as Maurice

Paul Bates as Oha

Samuel L. Jackson as Hold-Up Man

Vanessa Bell Calloway as Imani Izzi

Calvin Lockhart as Colonel Izzi

Vondie Curtis-Hall as Basketball Game Vendor

Cuba Gooding Jr. as Boy Getting Haircut

Feather as Rose Bearer #1

Stephanie Simon as Rose Bearer #2

Garcelle Beauvais as Rose Bearer #3

Ruben Santiago-Hudson as Street Hustler

Birdie M. Hale as Elderly Passenger

Clyde Jones as Soul Glo Man

Jim Abrahams as Face on Cutting Room Floor

Victoria Dillard as Bather / Dancer

Felicia Taylor as Bather

Midori as Bather

Sheila Johnson as Lady-in-Waiting

Jake Steinfeld as Cab Driver

Clint Smith as Sweets

Uncle Ray Murphy as Stu

Paulette Banoza as Soul Glo Woman

Patricia Matthews as Devil Woman

Mary Bond Davis as Big Stank Woman

Carla Earle as Tough Girl

Karen Owens as Ex-Siamese Twin / Dancer

Sharon Owens as Ex-Siamese Twin / Dancer

Lisa Gumora as Kinky Girl

June Boykins as Strange Woman

Janette Colon as Fresh Peaches

Vanessa Colon as Sugar Cube

Monique Mannen as Boring Girl / Dancer

Mindora Mimms as Awareness Woman

Cynthia Finkley as Awareness Woman

David Sosna as Cartier Delivery Man

Arthur Adams as Mr. Jenks

Loni Kaye Harkless as Mrs. Jenks

Montrose Hagins as Grandma Jenks

Tonja Rivers as Party Guest

Ralph Bellamy as Randolph Duke / Homeless Man #1 (uncredited)

Don Ameche as Mortimer Duke / Homeless Man #2 (uncredited)

Karl Denson as 'Sexual Chocolate' Saxophonist (uncredited)

Elaine Kagan as Telegraph Lady (uncredited)

Michael Tadross as Taxi Driver (uncredited)

Steve White as Subway Guy (uncredited)

Helen Hanft as Subway Lady (uncredited)

Leah Aldridge as Dancer (uncredited)

Aurorah Allain as Dancer (uncredited)

Paula Brown as Dancer (uncredited)

Dwayne Chattman as Dancer (uncredited)

Stephanie Clark as Dancer (uncredited)

Robin L. Dimension as Dancer (uncredited)

Shaun Earl as Dancer (uncredited)

Eric L. Ellis as Dancer (uncredited)

Sharon Ferrol-Young as Dancer (uncredited)

Eric D. Henderson as Dancer (uncredited)

Gigi Hunter as Dancer (uncredited)

Debra Johnson as Dancer (uncredited)

Tanya Lynne Lee as Dancer (uncredited)

Jimmy Locust as Dancer (uncredited)

Donna M. Perkins as Dancer (uncredited)

Dionne Rockhold as Dancer (uncredited)

Gina Consuela Rose as Dancer (uncredited)

Randolph Scott as Dancer (uncredited)

Robbin Tasha-Ford as Dancer (uncredited)

Jerald Vincent as Dancer (uncredited)

Eyan Williams as Dancer (uncredited)

Roy Milton Davis as Homeless Man Around Garbage Can Bonfire (uncredited)

Dorian DeMichele as Viola (uncredited)

Alison Gordy as Blond Hooker / Bag Lady in Fast Food Place (uncredited)

Mary Young as Stuck-Up Girl (uncredited)

Tobe Hooper as Party Guest (uncredited)

Raymond D. Turner as T-Shirt Hawker