Eddie Murphy as Norbit / Rasputia / Mr. Wong

Thandiwe Newton as Kate Thomas

Terry Crews as Big Jack Latimore

Clifton Powell as Earl Latimore

Lester Speight as Blue Latimore

Cuba Gooding Jr. as Deion Hughes

Katt Williams as Lord Have Mercy

Marlon Wayans as Buster

Eddie Griffin as Pope Sweet Jesus

Richard Gant as Preacher

Floyd Levine as Abe the Tailor

Anthony Russell as Giovanni

Pat Crawford Brown as Mrs. Henderson

Jeanette Miller as Mrs. Coleman

Michael Colyar as Morris the Barber

Alexis Rhee as Mrs. Ling Ling Wong

Rob Huebel as Excited Man on TV

John J West as Choir Member

John Gatins as Attendant

Khamani Griffin as Norbit - Age 5

Lindsey Sims-Lewis as Rasputia - Age 10

China Anderson as Kate - Age 5

Kristen Schaal as Event Organizer

Susan Beaubian as Shop Owner

Charlie Murphy as Floyd the Dog (voice)

Hayley Marie Norman as Ex-Wife

Sara Sanderson as Ex-Wife

Smith Cho as Ex-Wife

Lonnie Henderson as Beautician

Marianne Muellerleile as Helga

Bruna Rubio as Stripper (uncredited)

Anastacia McPherson as Waitress (Uncredited)

Donna Medine as Choir Member