Jessica Chastain as Eleanor Rigby

James McAvoy as Conor Ludlow

Bill Hader as Stuart

Viola Davis as Professor Lillian Friedman

Isabelle Huppert as Mary Rigby

Ciarán Hinds as Spencer Ludlow

Nina Arianda as Alexis

Jess Weixler as Katy Rigby

William Hurt as Julian Rigby

Ryan Eggold as Guy from Club

Jeremy Shamos as Evangelist

Nikki M. James as Sia

Wyatt Ralff as Philip

Brendan Donaldson as Casimir Waiter

Daron Stewart as Guy Walking on Bridge

Julee Cerda as Nurse

Sasha Eden as Coffee Truck Barista

Johnathan Fernandez as Bar Fight Guy

Justine Salata as Bar Fight Girl

Musto Pelinkovicci as Ukrainian Cabbie

Rafael Feldman as Paramedic

Michael T. King as Paramedic

Jimmy Palumbo as Rental Car Attendant

Will Beinbrink as Gary the Dentist

Marta Milans as Phoebe

Maxfield Lund as Analytical Guy (uncredited)