Kate Higgins as Frankie Stein (voice)

Debi Derryberry as Draculaura (voice)

Salli Saffioti as Clawdeen Wolf / Cleo de Nile (voice)

Laura Bailey as Lagoona Blue (voice)

Erin Fitzgerald as Abbey Bominable / C.A. Cupid / Rochelle Goyle / Spectra (voice)

Ogie Banks as Clawd Wolf (voice)

Evan Smith as Deuce Gorgon / Gil Webber / Bram Devein / Rocco (voice)

Audu Paden as Ghoulia Yelps / Manny Taur / Announcer / Nightmare (voice)

America Young as Toralei / Howleen Wolf (voice)

Julie Maddalena as Robecca Steam / Venus McFlytrap (voice)

Cam Clarke as Heath Burns / Romulus (voice)

Cindy Robinson as Jackson Jekyll / Operetta (voice)

Andrew Duncan as Gary (voice)

Ira Singerman as Eye-ra (voice)