Donald Sutherland as Dr. Norman Bethune

Helen Mirren as Frances Penny Bethune

Helen Shaver as Mrs. Dowd

Colm Feore as Chester Rice

James Pax as Mr. Tung

Guo Da as Dr. Chan

Anouk Aimée as Marie-France Coudaire

Ronald Pickup as Alan Coleman

Geoffrey Chater as Dr. Archibald

Tan Zongyao as General Nieh

Zhang Ke Yaw as Chairman Mao

Iñaki Aierra as Dr. Salvador

Li Hai Lang as Shiao

Yvan Ponton as Frank Coudaire

Sophie Faucher as Nurse Mackenzie

Danute Kristo as Ingrid Halstrom

Béatrice Home as Mary

Nicholas Kilbertus as George Pilling

Linda O'Dwyer as Nursing Sister

Frank Fontaine as Dr. Williamson

Régent Gauvin as cobbler

Lorne Brass as photographer

David Francis as Pilling Associate

Michael Sinelnikoff as Conference Doctor

Norris Domingue as Business Man

Timothy Webber as Reporter

Xang Xing Junh as Cook Wu

Wang Chun Yen as Prisoner's Wife

Liu Yun Chai as Prisoner

Sang Dexin as Bellhop

Huo Jin Yu as Nationalist Officer

Wang Xing Jun as Liu (8th Route Army Soldier)

Chen Da Wei as Wang (8th Route Army Soldier)

James Hong as

Yan Xiaopeng as 旅馆老板

Harrison Liu as Dr. Fong

Zhang Keyao as 毛泽东

Yi Liu as 刘叶